Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid

ABSTRACT Poorly differentiated primary pulmonary synovial sarcomas are rare and challenging for a surgical pathologist to diagnose. Although the demonstration of the tumor specific translocation, t (x; 18)(p11.2;q11.2) or the resultant fusion gene (SYT-SSX) is the gold standard for diagnosis, this t...

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Bibliographic Details
Published in:Journal of laboratory physicians 2013-01, Vol.5 (1), p.55-57
Main Authors: Kaur, Amulyajit, Tazelaar, Henry Dale, Sahai, Kavita
Format: Article
Language:English
Subjects:
Case Report
Diagnosis
Immunohistochemistry
lung
Sarcoma
synovial sarcoma
transducer-like enhancer of split-1
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Summary:ABSTRACT Poorly differentiated primary pulmonary synovial sarcomas are rare and challenging for a surgical pathologist to diagnose. Although the demonstration of the tumor specific translocation, t (x; 18)(p11.2;q11.2) or the resultant fusion gene (SYT-SSX) is the gold standard for diagnosis, this test is not always accessible. We report the use of immunohistochemistry, including transducer-like enhancer of split-1 in the diagnosis of one such tumor in a young individual.
ISSN:0974-2727
0974-7826
DOI:10.4103/0974-2727.115922