A Study Comparing Centchroman and Evening Primrose Oil in the Treatment of Benign Breast Disease

Females seeking medical attention at breast clinics commonly present with nonmalignant breast conditions, including nonspecific breast pain or distinct masses like fibroadenomas. Due to its variability, it may be difficult to quantify breast pain. The purpose of the research was to compare centchrom...

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Bibliographic Details
Published in:Journal of pharmacy & bioallied science 2024-04, Vol.16 (Suppl 2), p.S1544-S1548
Main Authors: Sinha, Nirupam, Tajdar, Yasir, Pankaj, Deepak, Kumar, Nitesh, Muni, Sweta, Bhushan, Vibhuti
Format: Article
Language:English
Subjects:
benign breast disease
Breast
Breast diseases
breast pain
Care and treatment
centchroman
Diseases
evening primrose oil
Fibroadenoma
India
Medical research
Medical treatment
Medicine, Experimental
Oils & fats
Original
Pain
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Summary:Females seeking medical attention at breast clinics commonly present with nonmalignant breast conditions, including nonspecific breast pain or distinct masses like fibroadenomas. Due to its variability, it may be difficult to quantify breast pain. The purpose of the research was to compare centchroman and evening primrose oil to identify a cost-effective, secure, and efficient treatment for benign breast disease. In this prospective hospital-based observational study, 100 breast diseases with or without lumpiness for 1 year were included and divided into two groups with 50 cases each, Group-A (Centchroman) and Group-B (Evening primrose oil). Centchroman exhibited a significantly greater treatment response for alleviating pain-free mastalgia compared to evening primrose oil. Additionally, centchroman showed an excellent response ( < .05). Among participants with mastalgia, centchroman significantly reduced the number of mastalgia patients with tender nodularity post-treatment ( = .035) than evening primrose oil. On the basis of fibroadenoma, partial and complete response was significantly seen in higher number of cases in the centchroman group ( = .007). Centchroman therapy demonstrates that the treatment for benign breast disease is safe, effective, and economical.
ISSN:0976-4879
0975-7406
DOI:10.4103/jpbs.jpbs_399_23