Advances in Hydrogel-Based Drug Delivery Systems

Hydrogels, with their distinctive three-dimensional networks of hydrophilic polymers, drive innovations across various biomedical applications. The ability of hydrogels to absorb and retain significant volumes of water, coupled with their structural integrity and responsiveness to environmental stim...

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Bibliographic Details
Published in:Gels 2024-04, Vol.10 (4), p.262
Main Authors: Liu, Boya, Chen, Kuo
Format: Article
Language:English
Subjects:
Biocompatibility
Biodegradation
Biomedical materials
Biopolymers
Chemistry
Crosslinking
Design
drug delivery
Drug delivery systems
Environmental engineering
Free radicals
Health aspects
Hyaluronic acid
hydrogel
Hydrogels
injectable
Innovations
ocular
oral
Physiology
Polymerization
Polymers
Regenerative medicine
Structural integrity
Tissue engineering
topical
Transdermal medication
Wound healing
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Summary:Hydrogels, with their distinctive three-dimensional networks of hydrophilic polymers, drive innovations across various biomedical applications. The ability of hydrogels to absorb and retain significant volumes of water, coupled with their structural integrity and responsiveness to environmental stimuli, renders them ideal for drug delivery, tissue engineering, and wound healing. This review delves into the classification of hydrogels based on cross-linking methods, providing insights into their synthesis, properties, and applications. We further discuss the recent advancements in hydrogel-based drug delivery systems, including oral, injectable, topical, and ocular approaches, highlighting their significance in enhancing therapeutic outcomes. Additionally, we address the challenges faced in the clinical translation of hydrogels and propose future directions for leveraging their potential in personalized medicine and regenerative healthcare solutions.
ISSN:2310-2861
2310-2861
DOI:10.3390/gels10040262