Impact of seasons on stroke-related depression, mediated by vitamin D status

This study aimed to describe the seasonal variation of depression prevalence among stroke patients at 1 month and to explore whether vitamin D plays a role in the association between seasons and post-stroke depression (PSD). Data were collected from 402 acute stroke patients. Seasons were stratified...

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Bibliographic Details
Published in:BMC psychiatry 2018-11, Vol.18 (1), p.359-359, Article 359
Main Authors: Gu, Yingying, Luan, Xiaoqian, Ren, Wenwei, Zhu, Lin, He, Jincai
Format: Article
Language:English
Subjects:
Biomarker
Care and treatment
Complications and side effects
Depression
Depression (Mood disorder)
Environmental aspects
Health aspects
Influence
Medical climatology
Mental depression
Mortality
Multivariate analysis
NMR
Nuclear magnetic resonance
Older people
Psychiatry
Regression analysis
Risk factors
Season
Seasonal variations
Seasons
Stroke
Vitamin D
Vitamin deficiency
Women
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Summary:This study aimed to describe the seasonal variation of depression prevalence among stroke patients at 1 month and to explore whether vitamin D plays a role in the association between seasons and post-stroke depression (PSD). Data were collected from 402 acute stroke patients. Seasons were stratified by summertime (June to November) and wintertime (December to May) based on vitamin D status. The impact of seasons on PSD was assessed via binary logistic regression, with summertime considered the referent category. The mediating effect was used to evaluate whether vitamin D plays a role in the association between seasons and PSD. The prevalence of PSD was significantly higher in the wintertime group than in the summertime group (P = 0.003). The serum vitamin D level was lower in wintertime than in summertime (P 
ISSN:1471-244X
1471-244X
DOI:10.1186/s12888-018-1944-z