In celebration of the 100th anniversary of the lipid hypothesis of atherosclerosis

This year marks the 100th anniversary of the publication of Anitschkow's classic paper proposing the central role of hypercholesterolemia in atherogenesis. We at the Journal of Lipid Research take this occasion to acknowledge the debt we all owe to Anitschkow and his colleagues for getting us o...

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Bibliographic Details
Published in:Journal of lipid research 2013-11, Vol.54 (11), p.2946-2949
Main Author: Steinberg, Daniel
Format: Article
Language:English
Subjects:
Animals
Atherosclerosis - blood
Atherosclerosis - history
Atherosclerosis - metabolism
Atherosclerosis - pathology
Cholesterol - blood
History, 20th Century
History, 21st Century
Humans
Models, Biological
Thematic Review
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Summary:This year marks the 100th anniversary of the publication of Anitschkow's classic paper proposing the central role of hypercholesterolemia in atherogenesis. We at the Journal of Lipid Research take this occasion to acknowledge the debt we all owe to Anitschkow and his colleagues for getting us on the right track. As discussed below in detail, his contributions were insightful and went well beyond simply pinpointing hypercholesterolemia as a major etiologic factor. Anitschkow's work led him to define most of the key elements in the initiation and evolution of lesions in animal models of atherogenesis.
ISSN:0022-2275
1539-7262
DOI:10.1194/jlr.R043414