Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China: A multicenter retrospective study

ABSTRACT Importance The clinical characteristics of infectious mononucleosis (IM) in Chinese children have not been evaluated in multicenter studies, and the effectiveness of antiviral treatment are controversial. Objective To investigate the clinical characteristics of Chinese children with IM and...

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Bibliographic Details
Published in:Pediatric investigation 2021-09, Vol.5 (3), p.188-194
Main Authors: Hu, Huili, Deng, Huiling, Bi, Jing, Xu, Yi, Li, Shuangjie, Xie, Yue, Sun, Xinrong, Wang, Dongmeng, Li, Xufang, Ouyang, Wenxian, Hu, Bing, Zhang, Yufeng, Tang, He, Fang, Chunxiao, Zhang, Hui, Guo, Lingyun, Wang, Chen, Wang, Tianyi, Yang, Fengxia, Jiang, Tao, Xie, Zhengde, Liu, Gang
Format: Article
Language:English
Subjects:
Abdomen
Acyclovir
Age groups
Antibodies
Antigens
Antiviral
Antiviral drugs
Asymptomatic
Edema
Epstein-Barr virus
Fever
Ganciclovir
Hospitalization
Hospitals
Infections
Infectious mononucleosis
Laboratories
Liver
Medical diagnosis
Medical records
Mononucleosis
Neutropenia
Original
Pain
Patients
Thrombocytopenia
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Summary:ABSTRACT Importance The clinical characteristics of infectious mononucleosis (IM) in Chinese children have not been evaluated in multicenter studies, and the effectiveness of antiviral treatment are controversial. Objective To investigate the clinical characteristics of Chinese children with IM and current status of antiviral therapy for affected patients. Methods Hospitalized patients with IM were enrolled between 2018 and 2020 in five children’s hospitals in China. The clinical characteristics were compared among four age groups:
ISSN:2574-2272
2096-3726
2574-2272
DOI:10.1002/ped4.12294