Loading…

Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone

Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive cohort study characterized real‐world rates o...

Full description

Saved in:
Bibliographic Details
Published in:Brain and behavior 2023-08, Vol.13 (8), p.e3171-n/a
Main Authors: Kern, David M., Canuso, Carla M., Daly, Ella, Johnson, Jonathan C., Fu, Dong Jing, Doherty, Teodora, Blauer‐Peterson, Cori, Cepeda, M. Soledad
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c5101-12409ade872b82d741abcb52062d1d6825f73580c95af30570d289d26bf1d2263
cites cdi_FETCH-LOGICAL-c5101-12409ade872b82d741abcb52062d1d6825f73580c95af30570d289d26bf1d2263
container_end_page n/a
container_issue 8
container_start_page e3171
container_title Brain and behavior
container_volume 13
creator Kern, David M.
Canuso, Carla M.
Daly, Ella
Johnson, Jonathan C.
Fu, Dong Jing
Doherty, Teodora
Blauer‐Peterson, Cori
Cepeda, M. Soledad
description Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive cohort study characterized real‐world rates of suicide‐specific mortality among patients with MDD with or without TRD or SI/SA. Methods Adult patients with MDD among commercially insured and Medicare enrollees in Optum Research Database were included and assigned to three cohorts: those with treatment‐resistant MDD (TRD), those with MDD and SI/SA (MDD+SI/SA), and those with MDD without TRD or SI/SA (MDD alone). Suicide‐specific mortality was obtained from the National Death Index. The effects of demographic characteristics and SI/SA in the year prior to the end of observation on suicide‐specific mortality were assessed. Results For the 139,753 TRD, 85,602 MDD+SI/SA, and 572,098 MDD alone cohort patients, mean age ranged from 55 to 59 years and the majority were female. At baseline, anxiety disorders were present in 53.92%, 44.11%, and 21.72% of patients with TRD, MDD+SI/SA, and MDD alone, respectively. Suicide‐mortality rates in the three cohorts were 0.14/100 person‐years for TRD, 0.27/100 person‐years for MDD+SI/SA, and 0.04/100 person‐years for MDD alone. SI/SA during the year prior to the end of observation, younger age, and male sex were associated with increased suicide risk. Conclusions Patients with TRD and MDD+SI/SA have a heightened risk of mortality by suicide compared with patients with MDD alone. Suicide rates were higher in patients with recent history versus older or no history of SI/SA, men versus women, and those of young age versus older age. This study examined nearly 800,000 patients with treatment resistant depression (TRD), major depressive disorder (MDD) with suicidal ideation/suicide attempt (MDD+SI/SA) and those with MDD without SI/SA or TRD (MDD alone). Suicide rates were 0.14/100 person‐years, 0.27/100 person‐years, and 0.04/100 person‐years in the TRD, MDD+SI/SA, and MDD alone cohorts, respectively. SI/SA during the last year of observation, younger age, and male sex were associated with increased suicide risk.
doi_str_mv 10.1002/brb3.3171
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_ee48d3f794b64e1da90c9a8a22676717</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_ee48d3f794b64e1da90c9a8a22676717</doaj_id><sourcerecordid>2857077989</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5101-12409ade872b82d741abcb52062d1d6825f73580c95af30570d289d26bf1d2263</originalsourceid><addsrcrecordid>eNp1ks1q3DAQgE1paUKaQ1-gCHppIZtIsmXZp5KE_gQChf6cxdgab7TYlitpE_bWR-ij9Rn6JJ3dTZeksL7Invn8aWaYLHsp-KngXJ41oclPc6HFk-xQilLOcqnrpw_eD7LjGBecHiUKWfDn2UGuC61UrQ-z31-XrnUW__z8FSdsXedaNviQoHdpxWDw45xNkByOKbI7l25YCghpoG_6JWB0McGY2AALH5jFiULR3SKzLvpgMZzsT219U3CUjpsyoGdUC13nR7YLIoOUcJhSPFkH9-ug9yO-yJ510Ec8vj-Psu8f3n-7_DS7_vzx6vL8etYqwcVM0CBqsFhp2VTS6kJA0zZK8lJaYctKqk7nquJtraDLudLcyqq2smw6YaUs86Psauu1HhaGmhggrIwHZzYBH-YGQnJtjwaxqGze6bpoygKFhZq0UAFpdKmFJte7rWtaNgPaloYboH8kfZwZ3Y2Z-1sjeKEKqSoyvLk3BP9jiTGZwcUW-x5G9MtoZFUITg3InNDX_6ELvwwjzYoo6lPruqqJerul2uBjDNjtqhHcrPfOrPfOrPeO2FcPy9-R_7aMgLMtcOd6XO03mYsvF_lG-RerK-mS</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2857077989</pqid></control><display><type>article</type><title>Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone</title><source>Open Access: PubMed Central</source><source>Wiley Online Library Open Access</source><source>Publicly Available Content Database</source><creator>Kern, David M. ; Canuso, Carla M. ; Daly, Ella ; Johnson, Jonathan C. ; Fu, Dong Jing ; Doherty, Teodora ; Blauer‐Peterson, Cori ; Cepeda, M. Soledad</creator><creatorcontrib>Kern, David M. ; Canuso, Carla M. ; Daly, Ella ; Johnson, Jonathan C. ; Fu, Dong Jing ; Doherty, Teodora ; Blauer‐Peterson, Cori ; Cepeda, M. Soledad</creatorcontrib><description>Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive cohort study characterized real‐world rates of suicide‐specific mortality among patients with MDD with or without TRD or SI/SA. Methods Adult patients with MDD among commercially insured and Medicare enrollees in Optum Research Database were included and assigned to three cohorts: those with treatment‐resistant MDD (TRD), those with MDD and SI/SA (MDD+SI/SA), and those with MDD without TRD or SI/SA (MDD alone). Suicide‐specific mortality was obtained from the National Death Index. The effects of demographic characteristics and SI/SA in the year prior to the end of observation on suicide‐specific mortality were assessed. Results For the 139,753 TRD, 85,602 MDD+SI/SA, and 572,098 MDD alone cohort patients, mean age ranged from 55 to 59 years and the majority were female. At baseline, anxiety disorders were present in 53.92%, 44.11%, and 21.72% of patients with TRD, MDD+SI/SA, and MDD alone, respectively. Suicide‐mortality rates in the three cohorts were 0.14/100 person‐years for TRD, 0.27/100 person‐years for MDD+SI/SA, and 0.04/100 person‐years for MDD alone. SI/SA during the year prior to the end of observation, younger age, and male sex were associated with increased suicide risk. Conclusions Patients with TRD and MDD+SI/SA have a heightened risk of mortality by suicide compared with patients with MDD alone. Suicide rates were higher in patients with recent history versus older or no history of SI/SA, men versus women, and those of young age versus older age. This study examined nearly 800,000 patients with treatment resistant depression (TRD), major depressive disorder (MDD) with suicidal ideation/suicide attempt (MDD+SI/SA) and those with MDD without SI/SA or TRD (MDD alone). Suicide rates were 0.14/100 person‐years, 0.27/100 person‐years, and 0.04/100 person‐years in the TRD, MDD+SI/SA, and MDD alone cohorts, respectively. SI/SA during the last year of observation, younger age, and male sex were associated with increased suicide risk.</description><identifier>ISSN: 2162-3279</identifier><identifier>EISSN: 2162-3279</identifier><identifier>DOI: 10.1002/brb3.3171</identifier><identifier>PMID: 37475597</identifier><language>eng</language><publisher>United States: John Wiley &amp; Sons, Inc</publisher><subject>Algorithms ; Antidepressants ; attempted suicide ; Codes ; Dementia ; Identification ; major depressive disorder ; Medicare ; Mental depression ; Mortality ; Original ; Patients ; Psychosis ; Psychotropic drugs ; Remission (Medicine) ; Self destructive behavior ; Suicidal behavior ; Suicidal ideation ; suicide ; Suicides &amp; suicide attempts ; treatment‐resistant depression</subject><ispartof>Brain and behavior, 2023-08, Vol.13 (8), p.e3171-n/a</ispartof><rights>2023 The Authors. published by Wiley Periodicals LLC.</rights><rights>2023 The Authors. Brain and Behavior published by Wiley Periodicals LLC.</rights><rights>2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5101-12409ade872b82d741abcb52062d1d6825f73580c95af30570d289d26bf1d2263</citedby><cites>FETCH-LOGICAL-c5101-12409ade872b82d741abcb52062d1d6825f73580c95af30570d289d26bf1d2263</cites><orcidid>0000-0001-5417-3925</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2857077989/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2857077989?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,11562,25753,27924,27925,37012,37013,44590,46052,46476,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37475597$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kern, David M.</creatorcontrib><creatorcontrib>Canuso, Carla M.</creatorcontrib><creatorcontrib>Daly, Ella</creatorcontrib><creatorcontrib>Johnson, Jonathan C.</creatorcontrib><creatorcontrib>Fu, Dong Jing</creatorcontrib><creatorcontrib>Doherty, Teodora</creatorcontrib><creatorcontrib>Blauer‐Peterson, Cori</creatorcontrib><creatorcontrib>Cepeda, M. Soledad</creatorcontrib><title>Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone</title><title>Brain and behavior</title><addtitle>Brain Behav</addtitle><description>Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive cohort study characterized real‐world rates of suicide‐specific mortality among patients with MDD with or without TRD or SI/SA. Methods Adult patients with MDD among commercially insured and Medicare enrollees in Optum Research Database were included and assigned to three cohorts: those with treatment‐resistant MDD (TRD), those with MDD and SI/SA (MDD+SI/SA), and those with MDD without TRD or SI/SA (MDD alone). Suicide‐specific mortality was obtained from the National Death Index. The effects of demographic characteristics and SI/SA in the year prior to the end of observation on suicide‐specific mortality were assessed. Results For the 139,753 TRD, 85,602 MDD+SI/SA, and 572,098 MDD alone cohort patients, mean age ranged from 55 to 59 years and the majority were female. At baseline, anxiety disorders were present in 53.92%, 44.11%, and 21.72% of patients with TRD, MDD+SI/SA, and MDD alone, respectively. Suicide‐mortality rates in the three cohorts were 0.14/100 person‐years for TRD, 0.27/100 person‐years for MDD+SI/SA, and 0.04/100 person‐years for MDD alone. SI/SA during the year prior to the end of observation, younger age, and male sex were associated with increased suicide risk. Conclusions Patients with TRD and MDD+SI/SA have a heightened risk of mortality by suicide compared with patients with MDD alone. Suicide rates were higher in patients with recent history versus older or no history of SI/SA, men versus women, and those of young age versus older age. This study examined nearly 800,000 patients with treatment resistant depression (TRD), major depressive disorder (MDD) with suicidal ideation/suicide attempt (MDD+SI/SA) and those with MDD without SI/SA or TRD (MDD alone). Suicide rates were 0.14/100 person‐years, 0.27/100 person‐years, and 0.04/100 person‐years in the TRD, MDD+SI/SA, and MDD alone cohorts, respectively. SI/SA during the last year of observation, younger age, and male sex were associated with increased suicide risk.</description><subject>Algorithms</subject><subject>Antidepressants</subject><subject>attempted suicide</subject><subject>Codes</subject><subject>Dementia</subject><subject>Identification</subject><subject>major depressive disorder</subject><subject>Medicare</subject><subject>Mental depression</subject><subject>Mortality</subject><subject>Original</subject><subject>Patients</subject><subject>Psychosis</subject><subject>Psychotropic drugs</subject><subject>Remission (Medicine)</subject><subject>Self destructive behavior</subject><subject>Suicidal behavior</subject><subject>Suicidal ideation</subject><subject>suicide</subject><subject>Suicides &amp; suicide attempts</subject><subject>treatment‐resistant depression</subject><issn>2162-3279</issn><issn>2162-3279</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp1ks1q3DAQgE1paUKaQ1-gCHppIZtIsmXZp5KE_gQChf6cxdgab7TYlitpE_bWR-ij9Rn6JJ3dTZeksL7Invn8aWaYLHsp-KngXJ41oclPc6HFk-xQilLOcqnrpw_eD7LjGBecHiUKWfDn2UGuC61UrQ-z31-XrnUW__z8FSdsXedaNviQoHdpxWDw45xNkByOKbI7l25YCghpoG_6JWB0McGY2AALH5jFiULR3SKzLvpgMZzsT219U3CUjpsyoGdUC13nR7YLIoOUcJhSPFkH9-ug9yO-yJ510Ec8vj-Psu8f3n-7_DS7_vzx6vL8etYqwcVM0CBqsFhp2VTS6kJA0zZK8lJaYctKqk7nquJtraDLudLcyqq2smw6YaUs86Psauu1HhaGmhggrIwHZzYBH-YGQnJtjwaxqGze6bpoygKFhZq0UAFpdKmFJte7rWtaNgPaloYboH8kfZwZ3Y2Z-1sjeKEKqSoyvLk3BP9jiTGZwcUW-x5G9MtoZFUITg3InNDX_6ELvwwjzYoo6lPruqqJerul2uBjDNjtqhHcrPfOrPfOrPeO2FcPy9-R_7aMgLMtcOd6XO03mYsvF_lG-RerK-mS</recordid><startdate>202308</startdate><enddate>202308</enddate><creator>Kern, David M.</creator><creator>Canuso, Carla M.</creator><creator>Daly, Ella</creator><creator>Johnson, Jonathan C.</creator><creator>Fu, Dong Jing</creator><creator>Doherty, Teodora</creator><creator>Blauer‐Peterson, Cori</creator><creator>Cepeda, M. Soledad</creator><general>John Wiley &amp; Sons, Inc</general><general>John Wiley and Sons Inc</general><general>Wiley</general><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-5417-3925</orcidid></search><sort><creationdate>202308</creationdate><title>Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone</title><author>Kern, David M. ; Canuso, Carla M. ; Daly, Ella ; Johnson, Jonathan C. ; Fu, Dong Jing ; Doherty, Teodora ; Blauer‐Peterson, Cori ; Cepeda, M. Soledad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5101-12409ade872b82d741abcb52062d1d6825f73580c95af30570d289d26bf1d2263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Algorithms</topic><topic>Antidepressants</topic><topic>attempted suicide</topic><topic>Codes</topic><topic>Dementia</topic><topic>Identification</topic><topic>major depressive disorder</topic><topic>Medicare</topic><topic>Mental depression</topic><topic>Mortality</topic><topic>Original</topic><topic>Patients</topic><topic>Psychosis</topic><topic>Psychotropic drugs</topic><topic>Remission (Medicine)</topic><topic>Self destructive behavior</topic><topic>Suicidal behavior</topic><topic>Suicidal ideation</topic><topic>suicide</topic><topic>Suicides &amp; suicide attempts</topic><topic>treatment‐resistant depression</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kern, David M.</creatorcontrib><creatorcontrib>Canuso, Carla M.</creatorcontrib><creatorcontrib>Daly, Ella</creatorcontrib><creatorcontrib>Johnson, Jonathan C.</creatorcontrib><creatorcontrib>Fu, Dong Jing</creatorcontrib><creatorcontrib>Doherty, Teodora</creatorcontrib><creatorcontrib>Blauer‐Peterson, Cori</creatorcontrib><creatorcontrib>Cepeda, M. Soledad</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Wiley Online Library website</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest Psychology Journals</collection><collection>ProQuest Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Brain and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kern, David M.</au><au>Canuso, Carla M.</au><au>Daly, Ella</au><au>Johnson, Jonathan C.</au><au>Fu, Dong Jing</au><au>Doherty, Teodora</au><au>Blauer‐Peterson, Cori</au><au>Cepeda, M. Soledad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone</atitle><jtitle>Brain and behavior</jtitle><addtitle>Brain Behav</addtitle><date>2023-08</date><risdate>2023</risdate><volume>13</volume><issue>8</issue><spage>e3171</spage><epage>n/a</epage><pages>e3171-n/a</pages><issn>2162-3279</issn><eissn>2162-3279</eissn><abstract>Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive cohort study characterized real‐world rates of suicide‐specific mortality among patients with MDD with or without TRD or SI/SA. Methods Adult patients with MDD among commercially insured and Medicare enrollees in Optum Research Database were included and assigned to three cohorts: those with treatment‐resistant MDD (TRD), those with MDD and SI/SA (MDD+SI/SA), and those with MDD without TRD or SI/SA (MDD alone). Suicide‐specific mortality was obtained from the National Death Index. The effects of demographic characteristics and SI/SA in the year prior to the end of observation on suicide‐specific mortality were assessed. Results For the 139,753 TRD, 85,602 MDD+SI/SA, and 572,098 MDD alone cohort patients, mean age ranged from 55 to 59 years and the majority were female. At baseline, anxiety disorders were present in 53.92%, 44.11%, and 21.72% of patients with TRD, MDD+SI/SA, and MDD alone, respectively. Suicide‐mortality rates in the three cohorts were 0.14/100 person‐years for TRD, 0.27/100 person‐years for MDD+SI/SA, and 0.04/100 person‐years for MDD alone. SI/SA during the year prior to the end of observation, younger age, and male sex were associated with increased suicide risk. Conclusions Patients with TRD and MDD+SI/SA have a heightened risk of mortality by suicide compared with patients with MDD alone. Suicide rates were higher in patients with recent history versus older or no history of SI/SA, men versus women, and those of young age versus older age. This study examined nearly 800,000 patients with treatment resistant depression (TRD), major depressive disorder (MDD) with suicidal ideation/suicide attempt (MDD+SI/SA) and those with MDD without SI/SA or TRD (MDD alone). Suicide rates were 0.14/100 person‐years, 0.27/100 person‐years, and 0.04/100 person‐years in the TRD, MDD+SI/SA, and MDD alone cohorts, respectively. SI/SA during the last year of observation, younger age, and male sex were associated with increased suicide risk.</abstract><cop>United States</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>37475597</pmid><doi>10.1002/brb3.3171</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-5417-3925</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2162-3279
ispartof Brain and behavior, 2023-08, Vol.13 (8), p.e3171-n/a
issn 2162-3279
2162-3279
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_ee48d3f794b64e1da90c9a8a22676717
source Open Access: PubMed Central; Wiley Online Library Open Access; Publicly Available Content Database
subjects Algorithms
Antidepressants
attempted suicide
Codes
Dementia
Identification
major depressive disorder
Medicare
Mental depression
Mortality
Original
Patients
Psychosis
Psychotropic drugs
Remission (Medicine)
Self destructive behavior
Suicidal behavior
Suicidal ideation
suicide
Suicides & suicide attempts
treatment‐resistant depression
title Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T13%3A22%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Suicide%E2%80%90specific%20mortality%20among%20patients%20with%20treatment%E2%80%90resistant%20major%20depressive%20disorder,%20major%20depressive%20disorder%20with%20prior%20suicidal%20ideation%20or%20suicide%20attempts,%20or%20major%20depressive%20disorder%20alone&rft.jtitle=Brain%20and%20behavior&rft.au=Kern,%20David%20M.&rft.date=2023-08&rft.volume=13&rft.issue=8&rft.spage=e3171&rft.epage=n/a&rft.pages=e3171-n/a&rft.issn=2162-3279&rft.eissn=2162-3279&rft_id=info:doi/10.1002/brb3.3171&rft_dat=%3Cproquest_doaj_%3E2857077989%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5101-12409ade872b82d741abcb52062d1d6825f73580c95af30570d289d26bf1d2263%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2857077989&rft_id=info:pmid/37475597&rfr_iscdi=true