Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function inhospitalized elderly patients

Ying-Shuo Huang, Ying-Chao Feng, Jian Zhang, Li Bai, Wei Huang, Min Li, Ying Sun Department of Geriatrics and Gerontology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China Objective: To evaluate the impact of chronic obstructive pulmonary disease (COP...

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Bibliographic Details
Published in:Clinical interventions in aging 2014-12, Vol.10, p.81-87
Main Authors: Huang YS, Feng YC, Zhang J, Bai L, Huang W, Li M, Sun Y
Format: Article
Language:English
Subjects:
Echocardiography
Elderly
Heart failure
Key Words: Chronic obstructive pulmonary disease
Left ventricular diastolic dysfunction
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Summary:Ying-Shuo Huang, Ying-Chao Feng, Jian Zhang, Li Bai, Wei Huang, Min Li, Ying Sun Department of Geriatrics and Gerontology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China Objective: To evaluate the impact of chronic obstructive pulmonary disease (COPD) on left ventricular (LV) diastolic function in hospitalized elderly patients.Methods: This was a case-control observational study of 148 consecutive hospitalized elderly patients (≥65years old): 73 subjects without COPD as controls and 75 patients with COPD. Mild-to-moderate COPD was defined as stages 1 and 2, while severe and very severe COPD was defined as stages 3 and 4, according to the Global Initiative for Chronic Obstructive Lung Disease guidelines. Clinical characteristics and echocardiographic parameters were analyzed and compared.Results: Compared with the control group, patients with COPD had a higher frequency of LV diastolic dysfunction and heart failure with preserved ejection fraction. Smoking frequency, frequency of cerebrovascular diseases and diabetes, and serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels were higher in the COPD group (all P
ISSN:1178-1998