Psoas muscle measurement as a marker of sarcopenia predicts risk of Grade 4 or 5 baseline chronic kidney disease and its progression

Background Psoas muscle area (PMA) has recently been found to be an appropriate surrogate for whole‐body skeletal muscle mass and a measure of sarcopenia. Sarcopenia, which includes a decreased muscle mass and correlated with physical disability, morbidity, and mortality, is prevalent in and has del...

Full description

Saved in:
Bibliographic Details
Published in:JCSM rapid communications 2022-07, Vol.5 (2), p.182-193
Main Authors: Yang, Davine, Iqbal, Sameena, Rafatzand, Khashayar, Scheede‐Bergdahl, Celena
Format: Article
Language:English
Subjects:
Abdomen
Acidosis
Blood
Body mass index
Chronic illnesses
Chronic kidney disease
Creatinine
Data collection
Diabetes
Disease progression
Heart rate
Hemoglobin
Hospitals
Kidney diseases
Laboratories
Metabolism
Mortality
Musculoskeletal system
Patients
Population
Proteins
Psoas muscle area
Risk factors
Risk prediction
Sarcopenia
Thyroid gland
Tomography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Psoas muscle area (PMA) has recently been found to be an appropriate surrogate for whole‐body skeletal muscle mass and a measure of sarcopenia. Sarcopenia, which includes a decreased muscle mass and correlated with physical disability, morbidity, and mortality, is prevalent in and has deleterious consequences for patients with chronic kidney disease (CKD). The current study investigates the association of PMA, as a marker of sarcopenia, with baseline kidney function and CKD progression. Methods A retrospective cohort study was conducted in a community hospital nephrology clinic setting. For this study, sarcopenia was defined as standardized PMA measured at the L3 level either as below 25th percentile or below the median. Progression of CKD was measured by estimated glomerular filtration rate (eGFR) decline rate and change in proteinuria. To assess sarcopenia as a predictor of baseline CKD Grade 4 or 5, a multivariate logistic regression model was applied using standardized PMA 
ISSN:2617-1619
2617-1619
DOI:10.1002/rco2.63