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Application of Pro-angiogenic Biomaterials in Myocardial Infarction

Biomaterials have potential applications in the treatment of myocardial infarction (MI). These biomaterials have the ability to mechanically support the ventricular wall and to modulate the inflammatory, metabolic, and local electrophysiological microenvironment. In addition, they can play an equall...

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Published in:ACS omega 2024-09, Vol.9 (36), p.37505-37529
Main Authors: Liang, Tingting, Liu, Jun, Liu, Feila, Su, Xiaohan, Li, Xue, Zeng, Jiao, Chen, Fuli, Wen, Heling, Chen, Yu, Tao, Jianhong, Lei, Qian, Li, Gang, Cheng, Panke
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container_end_page 37529
container_issue 36
container_start_page 37505
container_title ACS omega
container_volume 9
creator Liang, Tingting
Liu, Jun
Liu, Feila
Su, Xiaohan
Li, Xue
Zeng, Jiao
Chen, Fuli
Wen, Heling
Chen, Yu
Tao, Jianhong
Lei, Qian
Li, Gang
Cheng, Panke
description Biomaterials have potential applications in the treatment of myocardial infarction (MI). These biomaterials have the ability to mechanically support the ventricular wall and to modulate the inflammatory, metabolic, and local electrophysiological microenvironment. In addition, they can play an equally important role in promoting angiogenesis, which is the primary prerequisite for the treatment of MI. A variety of biomaterials are known to exert pro-angiogenic effects, but the pro-angiogenic mechanisms and functions of different biomaterials are complex and diverse, and have not yet been systematically described. This review will focus on the pro-angiogenesis of biomaterials and systematically describe the mechanisms and functions of different biomaterials in promoting angiogenesis in MI.
doi_str_mv 10.1021/acsomega.4c04682
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title Application of Pro-angiogenic Biomaterials in Myocardial Infarction
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