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Role of Sulfur Compounds in Garlic as Potential Therapeutic Option for Inflammation and Oxidative Stress in Asthma
Asthma is a chronic inflammatory disease in the airways with a multifactorial origin but with inflammation and oxidative stress as related pathogenic mechanisms. Garlic ( ) is a nutraceutical with different biological properties due to sulfur-containing natural compounds. Studies have shown that sev...
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| Published in: | International journal of molecular sciences 2022-12, Vol.23 (24), p.15599 |
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| Main Authors: | , , , , , , |
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| cites | cdi_FETCH-LOGICAL-c481t-2689fed19e61675cad282e93bc37008f917a9504d084aa41b5b88db296560e8a3 |
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| container_issue | 24 |
| container_start_page | 15599 |
| container_title | International journal of molecular sciences |
| container_volume | 23 |
| creator | Sánchez-Gloria, José L Rada, Karla M Juárez-Rojas, Juan G Sánchez-Lozada, Laura G Rubio-Gayosso, Ivan Sánchez-Muñoz, Fausto Osorio-Alonso, Horacio |
| description | Asthma is a chronic inflammatory disease in the airways with a multifactorial origin but with inflammation and oxidative stress as related pathogenic mechanisms. Garlic (
) is a nutraceutical with different biological properties due to sulfur-containing natural compounds. Studies have shown that several compounds in garlic may have beneficial effects on cardiovascular diseases, including those related to the lungs. Therefore, it is possible to take advantage of the compounds from garlic as nutraceuticals for treating lung diseases. The objective of this article is to review the biological properties of the sulfur compounds present in garlic for the treatment of asthma, as well as the cellular mechanisms involved. Here, we discuss the potential therapeutic effects of garlic compounds in the modulation of inflammation and oxidative stress, as well as its antibiotic and antiviral activities for identifying and testing potential treatment options for asthma management. |
| doi_str_mv | 10.3390/ijms232415599 |
| format | article |
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) is a nutraceutical with different biological properties due to sulfur-containing natural compounds. Studies have shown that several compounds in garlic may have beneficial effects on cardiovascular diseases, including those related to the lungs. Therefore, it is possible to take advantage of the compounds from garlic as nutraceuticals for treating lung diseases. The objective of this article is to review the biological properties of the sulfur compounds present in garlic for the treatment of asthma, as well as the cellular mechanisms involved. Here, we discuss the potential therapeutic effects of garlic compounds in the modulation of inflammation and oxidative stress, as well as its antibiotic and antiviral activities for identifying and testing potential treatment options for asthma management.</description><subject>Allergens</subject><subject>Allergies</subject><subject>Allium sativum</subject><subject>Antibiotics</subject><subject>Antioxidants</subject><subject>Antioxidants - pharmacology</subject><subject>Asthma</subject><subject>Asthma - drug therapy</subject><subject>Bacterial infections</subject><subject>Biological properties</subject><subject>Cardiovascular diseases</subject><subject>Chemical compounds</subject><subject>Chronic illnesses</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Cytokines</subject><subject>Functional foods & nutraceuticals</subject><subject>Garlic</subject><subject>Health services</subject><subject>Humans</subject><subject>Immunoglobulins</subject><subject>Inflammation</subject><subject>Inflammation - 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Garlic (
) is a nutraceutical with different biological properties due to sulfur-containing natural compounds. Studies have shown that several compounds in garlic may have beneficial effects on cardiovascular diseases, including those related to the lungs. Therefore, it is possible to take advantage of the compounds from garlic as nutraceuticals for treating lung diseases. The objective of this article is to review the biological properties of the sulfur compounds present in garlic for the treatment of asthma, as well as the cellular mechanisms involved. Here, we discuss the potential therapeutic effects of garlic compounds in the modulation of inflammation and oxidative stress, as well as its antibiotic and antiviral activities for identifying and testing potential treatment options for asthma management.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36555240</pmid><doi>10.3390/ijms232415599</doi><orcidid>https://orcid.org/0000-0001-8864-2304</orcidid><orcidid>https://orcid.org/0000-0001-6556-1632</orcidid><orcidid>https://orcid.org/0000-0002-9238-4202</orcidid><orcidid>https://orcid.org/0000-0003-0348-9617</orcidid><orcidid>https://orcid.org/0000-0001-8315-8572</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Allergens Allergies Allium sativum Antibiotics Antioxidants Antioxidants - pharmacology Asthma Asthma - drug therapy Bacterial infections Biological properties Cardiovascular diseases Chemical compounds Chronic illnesses Chronic obstructive pulmonary disease Cytokines Functional foods & nutraceuticals Garlic Health services Humans Immunoglobulins Inflammation Inflammation - drug therapy Inflammatory diseases Lung diseases Medical prognosis Nitric oxide Oxidative Stress Pathology Pharmacology Plant Extracts - pharmacology Respiratory diseases Review Steroids Streptococcus infections Sulfur Sulfur compounds Sulfur Compounds - pharmacology |
| title | Role of Sulfur Compounds in Garlic as Potential Therapeutic Option for Inflammation and Oxidative Stress in Asthma |
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