Investigation of the Possible Correlation between Idiopathic Parkinson’s Disease and Diabetes Mellitus in Egyptian Patients: A Pilot Study

Objectives. To study the diabetes-Parkinson's disease (PD) linkage. Methods. The investigators recorded the rapid eye movement sleep behavior disorder screening questionnaire (RBDSQ) score for 60 diabetic patients: 30 patients were treated with metformin-inclusive sulfonylurea and 30 patients w...

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Bibliographic Details
Published in:Neurology research international 2021, Vol.2021, p.2838669-10
Main Authors: AwadAllah Elgnainy, Afnan, Hamed, Mohammad Ismail, Osman Mohamed, Wael, Sabri, Nagwa Ali
Format: Article
Language:English
Subjects:
Blood sugar
Care and treatment
Diabetics
Glucose tolerance tests
Medical research
Medicine, Experimental
Type 2 diabetes
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Summary:Objectives. To study the diabetes-Parkinson's disease (PD) linkage. Methods. The investigators recorded the rapid eye movement sleep behavior disorder screening questionnaire (RBDSQ) score for 60 diabetic patients: 30 patients were treated with metformin-inclusive sulfonylurea and 30 patients were treated with sulphonylurea(s) monotherapy and matched with 30 controls. We evaluated blood glucose kinetics during a 75 g oral glucose tolerance test for (22) nondiabetic parkinsonian patients and (10) controls. The motor complications scores were recorded for all parkinsonian patients using the relevant parts of the Unified Parkinson’s Disease Rating Scale (UPDRS) part IV. Results. Diabetics recorded higher scores of RBDSQ than controls (p
ISSN:2090-1852
2090-1860
DOI:10.1155/2021/2838669