The Roles of Junctional Adhesion Molecules (JAMs) in Cell Migration

The review briefly summarizes the role of the family of adhesion molecules, JAMs (junctional adhesion molecules), in various cell migration, covering germ cells, epithelial cells, endothelial cells, several leukocytes, and different cancer cells. These functions affect multiple diseases, including r...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in cell and developmental biology 2022-03, Vol.10, p.843671-843671
Main Authors: Wang, Junqi, Liu, Han
Format: Article
Language:English
Subjects:
Cell and Developmental Biology
cell migration
endothelial cells
epithelial cells
germ cell
junctional adhesion molecules
leukocytes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The review briefly summarizes the role of the family of adhesion molecules, JAMs (junctional adhesion molecules), in various cell migration, covering germ cells, epithelial cells, endothelial cells, several leukocytes, and different cancer cells. These functions affect multiple diseases, including reproductive diseases, inflammation-related diseases, cardiovascular diseases, and cancers. JAMs bind to both similar and dissimilar proteins and take both similar and dissimilar effects on different cells. Concluding relevant results provides a reference to further research.
ISSN:2296-634X
2296-634X
DOI:10.3389/fcell.2022.843671