Expression of Calretinin Expression in Odontogenic Cysts and Odontogenic Tumors - Original Research

The present study was conducted for assessing variability in calretinin expression among odontogenic cysts as well as tumor cases. Fifteen cases were included in the present research consisting of cases like - dentigerous cyst, odontogenic keratocyst, apical radicular cyst along with tumors like ame...

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Bibliographic Details
Published in:Journal of pharmacy & bioallied science 2024-02, Vol.16 (Suppl 1), p.S227-S229
Main Authors: Pabbaraju, Srinivasulu, Boddeda, Kondala R, Sankurathree, Sravani, Menon, Ipseeta, Rai, Narendra P, Nagella, Sai P
Format: Article
Language:English
Subjects:
Ameloblastoma
Calretinin
Cysts
Immunohistochemistry
odontogenic cyst and tumors
Odontogenic tumors
Original
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Summary:The present study was conducted for assessing variability in calretinin expression among odontogenic cysts as well as tumor cases. Fifteen cases were included in the present research consisting of cases like - dentigerous cyst, odontogenic keratocyst, apical radicular cyst along with tumors like ameloblastoma, ameloblastic carcinoma, adenomatoid odontogenic tumor. Calretinin antibody was used for immunohistochemical staining. The amount of expression of this calretinin was statistically analyzed with the help of Chi-square test where < 0.05 was considered noteworthy statistically. Most cases of ameloblastomas were highly positive for calretinin expression as compared to other cysts and tumors. Therefore, the correlation of this variation of expression of calretinin was statistically noteworthy ( = 0.00). In this study, we concluded that for ameloblastomas, calretinin can be a specific marker immunohistochemically and can help in identifying the amount of aggressive spread of various odontogenic tumors.
ISSN:0976-4879
0975-7406
DOI:10.4103/jpbs.jpbs_469_23