Ketamine-propofol sedation in circumcision

• Published in: Brazilian journal of anesthesiology (Elsevier) 2015-09, Vol.65 (5), p.367-370
• Main Authors: Gulec, Handan, Sahin, Saziye, Ozayar, Esra, Degerli, Semih, Bercin, Fatma, Ozdemir, Osman
• Format: Article
• Language: eng ; por
• ISSN: 0104-0014; 1806-907X; 0104-0014

to compare the therapeutic effects of ketamine alone or ketamine plus propofol on analgesia, sedation, recovery time, side effects in premedicated children with midazolam-ketamine-atropin who are prepared circumcision operation. 60 American Society of Anaesthesiologists physical status I-II children, aged between 3 and 9 years, undergoing circumcision operations under sedation were recruited according to a randomize and double-blind institutional review board-approved protocol. Patients were randomized into two groups via sealed envelope assignment. Both groups were administered a mixture of midazolam 0.05mg/kg+ketamine 3mg/kg+atropine 0.02mg/kg intramuscularly in the presence of parents in the pre-operative holding area. Patients were induced with propofol-ketamine in Group I or ketamine alone in Group II. in the between-group comparisons, age, weight, initial systolic blood pressure, a difference in terms of the initial pulse rate was observed (p>0.050). Initial diastolic blood pressure and subsequent serial measurements of 5, 10, 15, 20thmin, systolic blood pressure, diastolic blood pressure and pulse rate in ketamine group were significantly higher (p