Intensified synthesis of palm olein designer lipids using sonication

• Published in: Ultrasonics sonochemistry 2021-05, Vol.73, p.105478-105478, Article 105478
• Main Authors: Jadhav, Harsh B., Gogate, Parag R., Waghmare, Jyotsna T., Annapure, Uday S.
• Format: Article
• Language: English
• Subjects: Designer lipids; Intensification; Long chain triglycerides; Medium chain fatty acid; Original; Ultrasound
• ISSN: 1350-4177; 1873-2828
• DOI: 10.1016/j.ultsonch.2021.105478

•Improved synthesis of designer lipids using acidolysis reaction between palm olein and caprylic acid.•Intensification based on the sonication with study into effect of different parameters.•Study on Reusability of Novozyme 435 in order to make process of intensification more economical.•Palm olein designer lipid demonstrated excellent oxidative stability. The present study deals with intensified synthesis of designer lipids with application of ultrasound based on biocatalyzed reaction between long chain triglyceride and medium chain fatty acid. The effects of various reaction conditions like molar ratio of reactant, reaction temperature, and enzyme loading along with the effect of ultrasound parameters such as duty cycle and irradiation time on the rate of formation of designer lipids has been investigated. The ultrasound assisted process was also compared with the traditional process so as to clearly bring out the intensification effects. During the study, it was clearly demonstrated that the optimum reaction conditions for maximum yield of designer lipids as 92% was molar ratio of medium chain fatty acid to long chain triglyceride as 4:1, reaction temperature of 40 °C, enzyme loading of 3%, duty cycle of 70%, 240 W as power dissipation and 360 min as reaction time. The recyclability study of enzyme showed its effectiveness up to 10 cycles. The synthesized designer lipid showed higher oxidative stability for 35 days and also showed Newtonian behaviour with eye appealing colour. The current study demonstrates development of an eco-friendly technique for intensified synthesis of designer lipids having numerous nutraceutical benefits.