Prevention strategies to identify LASA errors: building and sustaining a culture of patient safety

• Published in: BMC health services research 2020-01, Vol.20 (1), p.63-63, Article 63
• Main Authors: Lizano-Díez, Irene, Figueiredo-Escribá, Carlos, Piñero-López, M Ángeles, Lastra, Cecilia F, Mariño, Eduardo L, Modamio, Pilar
• Format: Article
• Language: English
• Subjects: Antidepressants; Brand names; Debate; Drug labeling; Drug Prescriptions; Drug safety; Drugs; Health policy; Health services; Hospitals; Humans; Industrial safety; Inpatients; Labeling; Licensing, certification and accreditation; Look-alike sound-alike; Marketing; Medical errors; Medication errors; Medication Errors - prevention & control; Names; Outpatients; Patient care; Patient Safety; Pharmaceuticals; Phonetics; Prescription writing; Prevention; Risk factors; Safety and security measures; Safety Management - organization & administration; Ticagrelor; Vendor relations; Vortioxetine; World health
• ISSN: 1472-6963; 1472-6963
• DOI: 10.1186/s12913-020-4922-3

Potential look-alike, sound-alike (LASA) errors in outpatient and inpatient prescriptions have been widely described worldwide. However, most strategies of reducing drug name confusion have been only focused on the processes of prescribing and dispensing, often following local rules. An illustrative recent example about this topic is given: the antidepressant Brintellix® (vortioxetine) (Takeda Pharmaceuticals USA, Inc.) and the antiplatelet medication Brilinta® (ticagrelor) (AstraZeneca LP). Revision of the initiatives that are currently applied to prevent potential LASA errors in different countries around the world and debate about the emerging strategies that could be implemented in short and mid-term. At present, a common policy worldwide on the authorization of unique names for innovative medicines does not exist. The implication of authorities in topdown strategies and the importance of developing an international health policy on the authorization of unique names for innovative medicines are highlighted in the following piece of opinion. Building and sustaining a culture of patient safety should be considered as a global top-down strategy which involved all the elements in the system (regulatory bodies, manufacturers and suppliers). The precedent established by the FDA in prevention strategies to identify and avoid LASA errors has been extremely important and should lead to international discussion. Coordinated international efforts are urgently needed in this area for the sake of patients' safety.