Evaluating posterior vitreous detachment by widefield 23-mm swept-source optical coherence tomography imaging in healthy subjects

Posterior vitreous detachment (PVD) is a separation between the posterior vitreous cortex and internal limiting membrane. Although PVD was historically considered an acute event, recent studies using spectral-domain optical coherence tomography (SD-OCT) revealed a gradual progression of PVD in healt...

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Bibliographic Details
Published in:Scientific reports 2021-10, Vol.11 (1), p.19754-19754, Article 19754
Main Authors: Chiku, Yoshiaki, Hirano, Takao, Takahashi, Yoshiaki, Tuchiya, Ayako, Nakamura, Marie, Murata, Toshinori
Format: Article
Language:English
Subjects:
692/308
692/699
Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Healthy Volunteers
Humanities and Social Sciences
Humans
Male
Middle Aged
multidisciplinary
Neuroimaging
Ophthalmoscopy
Science
Science (multidisciplinary)
Severity of Illness Index
Tomography
Tomography, Optical Coherence - methods
Tomography, Optical Coherence - standards
Vitreous Body
Vitreous Detachment - diagnosis
Young Adult
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Summary:Posterior vitreous detachment (PVD) is a separation between the posterior vitreous cortex and internal limiting membrane. Although PVD was historically considered an acute event, recent studies using spectral-domain optical coherence tomography (SD-OCT) revealed a gradual progression of PVD in healthy subjects. Although SD-OCT improved PVD studies, the narrow imaging angle and long examination time were problematic to allow wide angle capture. The Xephilio OCT-S1 (Canon), a swept-source OCT (SS-OCT) device, can obtain up to 23-mm of widefield B-scan images in a single acquisition. We used this widefield SS-OCT to quantitatively evaluate the PVD stage in 214 healthy subjects aged 4–89 years and determine whether PVD stages differ between the bilateral eyes of each patient. Age was significantly positively correlated with the overall PVD stage (ρ = 0.7520, P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-99372-z