Bariatric surgery as a treatment for pseudotumor cerebri: case study and narrative review of the literature

• Published in: São Paulo medical journal 2018-03, Vol.136 (2), p.182-187
• Main Authors: Cazzo, Everton, Gestic, Martinho Antonio, Utrini, Murillo Pimentel, Mendonça Chaim, Felipe David, Mendonça Chaim, Fábio Henrique, Cândido, Elaine Cristina, da Silveira Jarolavsky, Luciana Bueno, de Almeida, Ana Maria Neder, Pareja, José Carlos, Chaim, Elinton Adami
• Format: Article
• Language: English
• Subjects: Bariatric surgery; Female; Gastric Bypass; Humans; Intracranial hypertension; Intracranial Hypertension - etiology; Intracranial Hypertension - surgery; MEDICINE, GENERAL & INTERNAL; Middle Aged; Obesity; Obesity, Morbid - complications; Obesity, Morbid - surgery; Papilledema - etiology; Papilledema - surgery; Pseudotumor cerebri; Pseudotumor Cerebri - etiology; Pseudotumor Cerebri - surgery; Treatment Outcome
• ISSN: 1516-3180; 1806-9460; 1806-9460
• DOI: 10.1590/1516-3180.2016.0305060117

Pseudotumor cerebri occurs when there is an increase in intracranial pressure without an underlying cause, usually leading to loss of vision. It is most commonly observed in obese women of child-bearing age. A 46-year-old woman presented at our service with idiopathic intracranial hypertension that had been diagnosed two years earlier, which had led to chronic refractory headache and an estimated 30% loss of visual acuity, associated with bilateral papilledema. She presented partial improvement of the headache with acetazolamide, but the visual loss persisted. Her intracranial pressure was 34 cmH2O. She presented a body mass index of 39.5 kg/m2, also associated with high blood pressure. Computed tomography of the cranium with endovenous contrast did not show any abnormalities. She underwent Roux-en-Y gastric bypass with uneventful postoperative evolution. One month following surgery, she presented a 24% excess weight loss. An ophthalmological examination revealed absence of visual loss and remission of the papilledema. There were no new episodes of headache following the surgery. There was also complete resolution of high blood pressure. The intracranial pressure decreased to 24 cmH2O, six months after the surgery. Although the condition is usually associated with obesity, there are few reports of bariatric surgery among individuals with pseudotumor cerebri. In cases studied previously, there was high prevalence of resolution or improvement of the disease following bariatric surgery. There is no consensus regarding which technique is preferable. Thus, further research is necessary in order to establish a specific algorithm.