Effect of opium consumption on cardiovascular diseases - a cross- sectional study based on data of Rafsanjan cohort study

There are differences of opinion about the beneficial or detrimental effects of opium consumption on cardiovascular diseases (CVDs). So, we aimed to study the association between opium use and CVDs. We used data obtained from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiolog...

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Bibliographic Details
Published in:BMC cardiovascular disorders 2021-01, Vol.21 (1), p.2-11, Article 2
Main Authors: Khalili, Parvin, Ayoobi, Fatemeh, Mohamadi, Maryam, Jamalizadeh, Ahmad, La Vecchia, Carlo, Esmaeili-Nadimi, Ali
Format: Article
Language:English
Subjects:
Addictions
Age
Bias
Body mass index
Cardiovascular diseases
Cholesterol
Cohort analysis
Coronary artery disease
Cross-sectional studies
Diabetes
Epidemiology
Health aspects
Heart attack
Heart attacks
Heart diseases
Heroin
Ischemia
Ischemic heart diseases
Laboratories
Lead content
Low density lipoprotein
Myocardial infarction
Myocardial ischemia
Opium habit
Opium use
Oral administration
Phosphatase
Population
Prospective epidemiological research studies in IrAN (PERSIAN)
Questionnaires
Regression analysis
Risk factors
Smoking
Sociodemographics
Triglycerides
Validation studies
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Summary:There are differences of opinion about the beneficial or detrimental effects of opium consumption on cardiovascular diseases (CVDs). So, we aimed to study the association between opium use and CVDs. We used data obtained from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiological research studies in IrAN (PERSIAN), with detailed, validated data on opium consumption and some other exposures. A total of 10,000 adults were enrolled in the study. Logistic regression models were used to assess the possible relationships of opium consumption with the prevalence of ischemic heart diseases (IHD) and myocardial infarction (MI). In this study, 9990 participants in the baseline phase of the Rafsanjan adult cohort study were included according to their completed questionnaire. Among all participants, 870 and 296 individuals were found to suffer from IHD and MI, respectively. Opium consumption was found to be relatively high in the RCS participants, especially in men (men = 2150 and women = 228). Opium use was associated with a higher odds of IHD and MI, with the adjusted odds ratios (95% CI) of 1.51 (1.22-1.86) and 1.79 (1.31-2.45), respectively. Also, dose-response increases were observed with the highest odds ratios in the 4th quartile for MI and IHD (p-values for trend
ISSN:1471-2261
1471-2261
DOI:10.1186/s12872-020-01788-4