Plasmonic gold nanoagents for cancer imaging and therapy

Gold nanoparticles (AuNPs) are a popular material in the field of nanoscience because of their excellent biocompatibility and unique physical and chemical properties, and have been widely used in the biomedical field. AuNPs have a simple preparation method, controllable shape and size, high electron...

Full description

Saved in:
Bibliographic Details
Published in:View (Beijing, China) China), 2021-10, Vol.2 (5), p.n/a
Main Authors: Fu, Qinrui, Zhang, Xuan, Song, Jibin, Yang, Huanghao
Format: Article
Language:English
Subjects:
Biocompatibility
Cancer therapies
Chemotherapy
Contrast agents
Drug delivery systems
gold nanoparticles
imaging
Lasers
Magnetic resonance imaging
Medical diagnosis
Nanomaterials
Nanoparticles
Radiation therapy
self‐assembly
Signal to noise ratio
theranostics
therapy
Tissues
Tumors
Ultrasonic imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Gold nanoparticles (AuNPs) are a popular material in the field of nanoscience because of their excellent biocompatibility and unique physical and chemical properties, and have been widely used in the biomedical field. AuNPs have a simple preparation method, controllable shape and size, high electron density and atomic number, superparamagnetic properties, and radiation sensitization effect, and their optical absorbance can be adjusted to the required biological window; thus, AuNPs are suitable for cancer imaging (photoacoustic imaging, computed tomography, and magnetic resonance imaging), photothermal therapy, and radiotherapy. AuNPs can also be used as carriers to load photosensitizers or chemotherapeutic agents, and therefore, can also be used in photodynamic therapy and chemotherapy. In summary, AuNPs and their assemblies can simultaneously realize cancer diagnosis and treatment, providing a new idea in the development of precision medical treatment. The review has summarized the biomedical applications of plasmonic gold nanoagents in cancer diagnosis, including NIR‐I PA imaging, NIR‐II PA imaging, ratiometric PA imaging, CT imaging, MRI and multi‐modal imaging; and in cancer therapies including PTT, PDT, radiotherapy, chemotherapy, and combined therapy.
ISSN:2688-3988
2688-268X
2688-268X
DOI:10.1002/VIW.20200149