The effect of cardiac phase on distractor suppression and motor inhibition in a stop-signal task

• Published in: Scientific reports 2024-12, Vol.14 (1), p.29847-16, Article 29847
• Main Authors: Marshall, Amanda C., Ren, Qiaoyue, Enk, Lioba, Liu, Junhui, Schütz-Bosbach, Simone
• Format: Article
• Language: English
• Subjects: 631/477; 631/477/2811; Adult; Attention; Attention - physiology; Brain - physiology; Cardiac cycle; Cognition & reasoning; Diastole - physiology; Distractor processing; EEG; Efficiency; EKG; Electrocardiography; Electroencephalography; Feedback; Female; Heart; Heart Rate - physiology; Humanities and Social Sciences; Humans; Information processing; Inhibition, Psychological; Interoception; Male; Motor inhibition; Motor task performance; multidisciplinary; Psychomotor Performance - physiology; Reaction Time - physiology; Science; Science (multidisciplinary); Sensorimotor integration; Systole - physiology; Young Adult
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-80742-2

Past work has shown that stimuli timed to the cardiac systole, the time at which heartbeat feedback is transmitted to the brain, can be more effectively selected from conflicting information. Here, we investigated how the temporal alignment of distracting information to different phases of the cardiac cycle impacts inhibitory performance on a stop-signal task. While participants received the go-cue and anticipated a potential stop-signal, we presented several moving dots on the screen. The dots’ change of movement direction was timed to occur 290 ms posterior to the R-peak (for cardiac systole) or right at the R-peak (for cardiac diastole) of in-time ECG recordings. In a third control condition, no distracting dots were shown. Behavioural results found participants were significantly better at inhibiting their motor response in systole relative to diastole distractor trials. Electrophysiological evidence found reduced P2 amplitudes for viewing the distractors and enhanced N2 amplitudes to the subsequent stop-signal in systole relative to diastole distractor trials. This indicated that systole bound distractors were suppressed more effectively than diastole bound ones which led to enhanced motor inhibition. Our results indicate that the brain shows greater visual selection efficiency for distracting information co-occurring with cardiac systole which has implications for enhanced motor processing at later stages of the trial sequence.