Association Between Myocarditis and Mortality in COVID-19 Patients in a Large Registry

To present a large registry data assessing the association between myocarditis and mortality in patients with severe acute respiratory syndrome coronavirus 2 infection. The researchers identified adult patients aged 18 to 90 years of age with coronavirus disease 2019 (COVID-19) diagnosis in the TriN...

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Published in:Mayo Clinic proceedings. Innovations, quality & outcomes quality & outcomes, 2022-04, Vol.6 (2), p.114-119
Main Authors: Annie, Frank H., Alkhaimy, Haytham, Nanjundappa, Aravinda, Elashery, Ahmad
Format: Article
Language:English
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Summary:To present a large registry data assessing the association between myocarditis and mortality in patients with severe acute respiratory syndrome coronavirus 2 infection. The researchers identified adult patients aged 18 to 90 years of age with coronavirus disease 2019 (COVID-19) diagnosis in the TriNetX (COVID-19 research network) database between January 20, 2020, and December 9, 2020. These patients were then divided into groups of those who had a positive myocarditis diagnosis and those who did not. The researchers compared all-cause mortality between propensity-matched pairs of patients in both groups. A total of 259,352 patients with COVID-19 diagnosis were included in the study. Of those patients, 383 (0.2%) had myocarditis diagnosis, whereas 258,969 (99.8%) did not have myocarditis diagnosis during their hospital stay. Patients were predominantly male in the myocarditis group (59.0% vs 45.0%, P
ISSN:2542-4548
2542-4548
DOI:10.1016/j.mayocpiqo.2021.12.006