Comparison of SensPERT® Leishmania rapid test with two other immunochromatographic tests for the diagnosis of canine visceral leishmaniasis in Brazil

In urban environments, dogs serve as the primary reservoir for visceral leishmaniasis (VL). Rapidly diagnosing canine VL through tests enables early treatment and a favorable prognosis. This study aimed to assess the diagnostic performance of the SensPERT® test kit (Dechra®), Alere® Leishmaniasis Ac...

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Bibliographic Details
Published in:Veterinary World 2024-06, Vol.17 (6), p.1307-1310
Main Authors: Pereira, Mariana Elisa, Neves, Maria Clara Bianchini, de Almeida, Arleana do Bom Parto Ferreira, Sousa, Valéria Régia Franco
Format: Article
Language:English
Subjects:
Dogs
immunochromatography
Kala-azar
leishmania infantum
reservoir
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Summary:In urban environments, dogs serve as the primary reservoir for visceral leishmaniasis (VL). Rapidly diagnosing canine VL through tests enables early treatment and a favorable prognosis. This study aimed to assess the diagnostic performance of the SensPERT® test kit (Dechra®), Alere® Leishmaniasis Ac test kit, and the rapid test dual path platform (TR-DPP®) Bio-Manguinhos in detecting VL. 30 serum samples from reactive VL dogs and 30 serum samples from healthy dogs were employed for assessing the sensitivity and specificity variation between SensPERT® test kit, Alere® Leishmaniasis Ac test kit, and rapid test dual platform - TR-DPP®. The SensPERT® test outperformed Alere® and TR-DPP® in terms of sensitivity, specificity, positive and negative predictive values and demonstrated near-perfect concordance with Alere® and substantial concurrence with TR-DPP®. The SensPERT® rapid test proved to be a promising test in the detection of VL in dogs.
ISSN:0972-8988
2231-0916
DOI:10.14202/vetworld.2024.1307-1310