International multicenter comparative trial of endoscopic ultrasonography-guided gastroenterostomy versus surgical gastrojejunostomy for the treatment of malignant gastric outlet obstruction

Abstract Background and study aims  EUS-guided gastroenterostomy (EUS-GE) is a novel procedure that potentially offers long-lasting luminal patency without the risk of tumor ingrowth/overgrowth. This study compared the clinical success, technical success, adverse events (AEs), length of hospital sta...

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Published in:Endoscopy International Open 2017-04, Vol.5 (4), p.E275-E281
Main Authors: Khashab, Mouen A., Bukhari, Majidah, Baron, Todd H., Nieto, Jose, El Zein, Mohamad, Chen, Yen-I, Chavez, Yamile Haito, Ngamruengphong, Saowanee, Alawad, Ahmad S., Kumbhari, Vivek, Itoi, Takao
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Language:English
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Summary:Abstract Background and study aims  EUS-guided gastroenterostomy (EUS-GE) is a novel procedure that potentially offers long-lasting luminal patency without the risk of tumor ingrowth/overgrowth. This study compared the clinical success, technical success, adverse events (AEs), length of hospital stay (LOHS) and symptom recurrence in EUS-GE versus SGJ. Methods  This was a multicenter international retrospective comparative study of EUS-GE and SGJ in patients with malignant gastric outlet obstruction (GOO) who underwent either EUS-GE or SGJ. EUS-GE was performed using lumen apposing metal stents. Results  A total of 93 patients with malignant GOO treated with either EUS-GE (n = 30) or SGJ (n = 63) were identified. Peritoneal carcinomatosis was present in 13 (43 %) patients in the EUS-GE group and 7 (11 %) patients in the SGJ group ( P  
ISSN:2364-3722
2196-9736
DOI:10.1055/s-0043-101695