Exploring the link: Sturge-Weber syndrome and pituitary macroadenomas: A case report and review

Sturge-Weber syndrome (SWS) is a rare congenital disorder marked by facial port-wine birthmarks, neurological impairments, and ocular anomalies. Our case report describes a 20-year-old man with SWS who presented with right-sided weakness, slurred speech, and oral dyskinesia. Laboratory studies demon...

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Bibliographic Details
Published in:Radiology case reports 2024-11, Vol.19 (11), p.5007-5012
Main Authors: Hashmi, Razi, Elmeligy, Mohamed, Fabian, Daniel, Mahtani, Arun, Farid, Meena, Kinfe, Meheret, Karroum, Paul, Piccione, GianPaolo, Mahmoud, Mahmoud, Albakri, Mohamed, Padda, Inderbir
Format: Article
Language:English
Subjects:
Endocrinology
Neurology
Pituitary Macroadenomas
Seizure
Sturge-Weber Syndrome
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Summary:Sturge-Weber syndrome (SWS) is a rare congenital disorder marked by facial port-wine birthmarks, neurological impairments, and ocular anomalies. Our case report describes a 20-year-old man with SWS who presented with right-sided weakness, slurred speech, and oral dyskinesia. Laboratory studies demonstrated elevated prolactin levels, and imaging confirmed a pituitary macroadenoma. While not well-documented, the association between SWS and pituitary macroadenomas is emerging based on current evidence. The potential link may involve embryological, genetic, or hormonal factors influencing the simultaneous development of these conditions. This case highlights the need for a thorough evaluation in patients with SWS, incorporating both neuroimaging and endocrine assessments to manage associated complications effectively. Further research is necessary to investigate the link between SWS and pituitary tumors. Establishing evidence-based guidelines for the screening and management of these patients will improve outcomes and provide a standardized approach to care.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2024.07.115