Serum TLR9 and NF-κB Biochemical Markers in Patients with Acute Pancreatitis on Admission

Aim. The aim of this study was to investigate the serum TLR9 and NF-κB levels in patients for the diagnosis and prognostication of AP in the emergency department. Methods. In the current study, we looked at the TLR9 and NF-κB pathways in a cohort of 45 acute pancreatitis patients and compared them w...

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Bibliographic Details
Published in:Emergency medicine international 2020, Vol.2020 (2020), p.1-6
Main Authors: Szarpak, Lukasz, Aydın, Hüseyin, Yurtbay, Sefa, Demirtaş, Esin, Ayan, Mustafa, Cebecioğlu, Kıvanç, Korkmaz, İlhan, Demirtas, Erdal, Yıldız, Şeymanur
Format: Article
Language:English
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Summary:Aim. The aim of this study was to investigate the serum TLR9 and NF-κB levels in patients for the diagnosis and prognostication of AP in the emergency department. Methods. In the current study, we looked at the TLR9 and NF-κB pathways in a cohort of 45 acute pancreatitis patients and compared them with the control group. We also divided the patient groups as mild-moderate or severe and compared the biomarker levels between the groups. Results. Of the patients with acute pancreatitis, 22 (49%) were male and 23 (51%) were female. The mean age of the patient group was 62 years, with a range of 25–95 years. The control group consisted of 19 (43.1%) male and 25 (56.9%) female patients. The serum TLR9 and NF-κB values were significantly higher than those of the control group [1104.44 ± 339.20 vs. 702.08 ± 203.94; p
ISSN:2090-2840
2090-2859
DOI:10.1155/2020/1264714