Prognostic value of liver biochemical parameters for COVID-19 mortality

Coronavirus disease 2019 (COVID-19) has brought great challenges to global public health. However, a comprehensive analysis of the relationship between liver biochemical parameters and COVID-19 mortality is quite limited. We searched the following electronic databases: PubMed, Embase, Cochrane Libra...

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Bibliographic Details
Published in:Annals of hepatology 2021-03, Vol.21, p.100279-100279, Article 100279
Main Authors: Ye, Lin, Chen, Bin, Wang, Yitong, Yang, Yi, Zeng, Jiling, Deng, Guangtong, Deng, Yuhao, Zeng, Furong
Format: Article
Language:English
Subjects:
Alanine Transaminase - blood
Aspartate Aminotransferases - blood
Biomarkers - blood
COVID-19
COVID-19 - enzymology
COVID-19 - mortality
Global Health
Humans
Liver biochemical parameters
Meta-analysis
Mortality
Original
Pandemics
Prognosis
SARS-CoV-2
Survival Rate - trends
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Summary:Coronavirus disease 2019 (COVID-19) has brought great challenges to global public health. However, a comprehensive analysis of the relationship between liver biochemical parameters and COVID-19 mortality is quite limited. We searched the following electronic databases: PubMed, Embase, Cochrane Library, Web of Science, Scopus, Wanfang and China National Knowledge Infrastructure database until May 5, 2020. STATA software was used for the statistical analyses. A total of 25 studies involving 5971 COVID-19 patients were included in our analysis. Compared with non-survivors, survivors had lower levels of aspartate aminotransferase (AST) (weighted mean difference [WMD]=−16.71U/L, 95%CI=[−21.03,−12.40], P
ISSN:1665-2681
2659-5982
1665-2681
DOI:10.1016/j.aohep.2020.10.007