mSphere of Influence: Deciphering purine auxotrophy in protozoan parasites

Bruno Martorelli Di Genova works in parasitology, focusing on metabolism. In this mSphere of Influence article, he reflects on how the articles "Metabolic Reprogramming during Purine Stress in the Protozoan Pathogen " and "Yeast-Based High-Throughput Screen Identifies Equilibrative Nu...

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Bibliographic Details
Published in:mSphere 2024-04, Vol.9 (4), p.e0000724
Main Author: Martorelli Di Genova, Bruno
Format: Article
Language:English
Subjects:
apicomplexan parasites
Auxotrophy
Commentary
Humans
Leishmania
Leishmania donovani
Leishmania donovani - drug effects
Leishmania donovani - metabolism
Metabolism
Nucleoside transporter
Parasites
Parasitic diseases
Parasitology
Plasmodium falciparum
Plasmodium falciparum - drug effects
Plasmodium falciparum - metabolism
Proteomics
Protozoa
purine metabolism
Purines - metabolism
Toxoplasma - metabolism
Toxoplasma gondii
Tropical diseases
Yeast
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Summary:Bruno Martorelli Di Genova works in parasitology, focusing on metabolism. In this mSphere of Influence article, he reflects on how the articles "Metabolic Reprogramming during Purine Stress in the Protozoan Pathogen " and "Yeast-Based High-Throughput Screen Identifies Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites" impacted him, informing his research strategies and understanding of metabolic flexibility in .
ISSN:2379-5042
2379-5042
DOI:10.1128/msphere.00007-24