Recurrent Severe Hypoglycemia Secondary to Benign Phyllodes Tumour of the Breast

Non-Islet Cell Tumor-induced hypoglycemia (NICTH) secondary to phyllodes tumour is extremely rare but potentially life threatening if not treated promptly. We report a case of a 46-year-old female without underlying diabetes mellitus who presented with a large breast tumor and recurrent severe sympt...

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Bibliographic Details
Published in:Journal of the ASEAN Federation of Endocrine Societies 2022-07, Vol.36 (2)
Main Authors: Hwee Ching Tee, Vijiya Mala Valayatham
Format: Article
Language:English
Subjects:
corticosteroids
hypoglycemia
insulin-like Growth Factor II
mastectomy
phyllodes tumor
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Summary:Non-Islet Cell Tumor-induced hypoglycemia (NICTH) secondary to phyllodes tumour is extremely rare but potentially life threatening if not treated promptly. We report a case of a 46-year-old female without underlying diabetes mellitus who presented with a large breast tumor and recurrent severe symptomatic hypoglycemia. Investigations supported the diagnosis of NICTH and the hypoglycemia only resolved after corticosteroids and mastectomy. This case highlights the importance of considering NICTH in the evaluation of patients with voluminous tumour and hypoglycemia.
ISSN:0857-1074
2308-118X
DOI:10.15605/jafes.036.02.16