Osteoarthritis, Exercise, and Tissue Engineering: A Stimulating Triad for Health Professionals

Osteoarthritis (OA) is a degenerative disease, promoted by abnormal chronic mechanical loading over the joint, for instance, due to excessive body mass. Patients frequently report pain, fatigue, and limitations in specific functional daily activities. Regarding the treatment of OA, two nonpharmacolo...

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Bibliographic Details
Published in:Journal of aging research 2019-01, Vol.2019 (2019), p.1-6
Main Authors: Morouço, Pedro G., Santos-Rocha, Rita, Fernandes, Cristiana
Format: Article
Language:English
Subjects:
Additive manufacturing
Aging
Arthritis
Biomedical materials
Care and treatment
Disease
Exercise therapy
Hydrogels
Medical personnel
Obesity
Osteoarthritis
Review
Tissue engineering
Trauma
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Summary:Osteoarthritis (OA) is a degenerative disease, promoted by abnormal chronic mechanical loading over the joint, for instance, due to excessive body mass. Patients frequently report pain, fatigue, and limitations in specific functional daily activities. Regarding the treatment of OA, two nonpharmacological options are available. However, it is not clear which type and intensity of exercise have better outcomes in treatment and how tissue engineering can be a promising field due to the mechanical load implants will suffer. The aims of this work were to investigate (1) the main characteristics, prevalence, and consequences of OA; (2) the exercise prescription guidelines and whether exercise interventions have a positive effect on OA treatment; and (3) the novel improvements on tissue engineering for OA treatment. Both patients and practitioners should be aware that benefits may come from prescribed and supervised exercise. Recent studies have highlighted that an optimal balance between exercise and nutritional income should be widely recommended. Regarding tissue engineering, significant steps towards the development of implants that mimic the native tissue have been taken. Thus, further studies should focus on the impact that exercise (repetitive loading) might have on cartilage regeneration. Finally, suggestions for future research were proposed.
ISSN:2090-2204
2090-2212
2090-2212
DOI:10.1155/2019/1935806