Rabbit targeted genomic sequences after heterologous hybridization using human exome

Causal mutations for major genes that underlie a broad range of morphological traits are often located within exons of genes that then affect protein functions. Non-model organism genetic studies are not easy to perform due to the lack of genome-wide molecular tools such as SNP genotyping array. Gen...

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Bibliographic Details
Published in:BMC research notes 2022-08, Vol.15 (1), p.1-282, Article 282
Main Authors: Iannuccelli, Nathalie, Sarry, Julien, Billon, Yvon, Aymard, Patrick, Helies, Virginie, Cabau, Cédric, Donnadieu, Cécile, Demars, Julie
Format: Article
Language:English
Subjects:
Analysis
Animal biology
Animals
Archives & records
Biochemistry, Molecular Biology
Biodiversity
Bioinformatics
Biotechnology
Capture
Data Note
Datasets
DNA sequencing
Efficiency
Exome
Exons
Feeds
Genetic aspects
Genetic polymorphisms
Genetics
Genomes
Genomics
Genotyping
Growth
Heterologous hybridization
Human
Hybrid animals
Hybridization
Life Sciences
Mutation
Nucleotide sequencing
Polymorphism
Rabbit
Rabbits
Single-nucleotide polymorphism
Strains (organisms)
Targeted DNA sequencing
Veterinary medicine and animal Health
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Summary:Causal mutations for major genes that underlie a broad range of morphological traits are often located within exons of genes that then affect protein functions. Non-model organism genetic studies are not easy to perform due to the lack of genome-wide molecular tools such as SNP genotyping array. Genotyping-By-Sequencing (GBS) methods offer an alternative. Consequently, we used this approach that is focused on the exome to target and identify major genes in rabbit populations.
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-022-06162-5