Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans

Purpose. To investigate the regenerative results obtained with the association of bone marrow aspirate concentrate using the Bone Marrow Aspirate Concentrate (BMAC) method to a xenogeneic bone graft (Bio-Oss) in sinus floor elevation. Materials and Methods. Using a randomized controlled study design...

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Bibliographic Details
Published in:International Journal of Biomaterials 2015-01, Vol.2015 (2015), p.3-9
Main Authors: Aloise, Antonio Carlos, de Macedo, Luis Guilherme Scavone, Oliveira, Thiago Altro de, Teixeira, Marcelo Lucchesi, Pasquali, Paulo José, Pelegrine, André Antonio
Format: Article
Language:English
Subjects:
Bone marrow
Care and treatment
Paranasal sinus diseases
Transplantation
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Summary:Purpose. To investigate the regenerative results obtained with the association of bone marrow aspirate concentrate using the Bone Marrow Aspirate Concentrate (BMAC) method to a xenogeneic bone graft (Bio-Oss) in sinus floor elevation. Materials and Methods. Using a randomized controlled study design in eight consecutive patients (age of 55.4 ± 9.2 years), 16 sinus floor lift procedures were performed with Bio-Oss alone (control group, CG, n=8) or combined with bone marrow aspirate concentrate obtained via the BMAC method (test group, TG, n=8). Six months after the grafting procedures, bone biopsies were harvested during implant placement and were analyzed by histomorphometry. Results. Histomorphometric analysis revealed a significantly higher amount (p
ISSN:1687-8787
1687-8795
DOI:10.1155/2015/121286