Comparison of initial learning algorithms for long short-term memory method on real-time respiratory signal prediction

• Published in: Frontiers in oncology 2023-01, Vol.13, p.1101225-1101225
• Main Authors: Sun, Wenzheng, Dang, Jun, Zhang, Lei, Wei, Qichun
• Format: Article
• Language: English
• Subjects: Glorot initializer; He initializer; initializer; long short-term memory; Oncology; radiation therapy; respiratory signals prediction
• ISSN: 2234-943X; 2234-943X
• DOI: 10.3389/fonc.2023.1101225

This study aimed to examine the effect of the weight initializers on the respiratory signal prediction performance using the long short-term memory (LSTM) model. Respiratory signals collected with the CyberKnife Synchrony device during 304 breathing motion traces were used in this study. The effectiveness of four weight initializers (Glorot, He, Orthogonal, and Narrow-normal) on the prediction performance of the LSTM model was investigated. The prediction performance was evaluated by the normalized root mean square error (NRMSE) between the ground truth and predicted respiratory signal. Among the four initializers, the He initializer showed the best performance. The mean NRMSE with 385-ms ahead time using the He initializer was superior by 7.5%, 8.3%, and 11.3% as compared to that using the Glorot, Orthogonal, and Narrow-normal initializer, respectively. The confidence interval of NRMSE using Glorot, He, Orthogonal, and Narrow-normal initializer were [0.099, 0.175], [0.097, 0.147], [0.101, 0.176], and [0.107, 0.178], respectively. The experiment results in this study indicated that He could be a valuable initializer in the LSTM model for the respiratory signal prediction.