Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review

Nowadays, various drugs on the market are becoming more and more resistant to numerous diseases, thus declining their efficacy for treatment purposes in human beings. Antibiotic resistance is one among the top listed threat around the world which eventually urged the discovery of new potent drugs fo...

Full description

Saved in:
Bibliographic Details
Published in:Marine drugs 2017-11, Vol.15 (11), p.354
Main Authors: Shah, Sayed Asmat Ali, Akhter, Najeeb, Auckloo, Bibi Nazia, Khan, Ishrat, Lu, Yanbin, Wang, Kuiwu, Wu, Bin, Guo, Yue-Wei
Format: Article
Language:English
Subjects:
Alkaloids
Antibiotic resistance
Antibiotics
Biodiversity
Biological properties
biological properties and applications
Cancer
Chemoresistance
Chemotherapy
Cyanobacteria
Disease resistance
Drug discovery
Drug resistance
Drugs
Fungicides
Immunosuppressive agents
Inflammation
Lipid metabolism
Lipids
Marine microorganisms
Medical treatment
Metabolites
Microorganisms
Natural products
Peptides
Polyketides
Properties
Review
Secondary metabolites
Terpenes
Tuberculosis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Nowadays, various drugs on the market are becoming more and more resistant to numerous diseases, thus declining their efficacy for treatment purposes in human beings. Antibiotic resistance is one among the top listed threat around the world which eventually urged the discovery of new potent drugs followed by an increase in the number of deaths caused by cancer due to chemotherapy resistance as well. Accordingly, marine cyanobacteria, being the oldest prokaryotic microorganisms belonging to a monophyletic group, have proven themselves as being able to generate pharmaceutically important natural products. They have long been known to produce distinct and structurally complex secondary metabolites including peptides, polyketides, alkaloids, lipids, and terpenes with potent biological properties and applications. As such, this review will focus on recently published novel compounds isolated from marine cyanobacteria along with their potential bioactivities such as antibacterial, antifungal, anticancer, anti-tuberculosis, immunosuppressive and anti-inflammatory capacities. Moreover, various structural classes, as well as their technological uses will also be discussed.
ISSN:1660-3397
1660-3397
DOI:10.3390/md15110354