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Gender Score Development in the Berlin Aging Study II : A Retrospective Approach

In addition to biological sex, gender, defined as the sociocultural dimension of being a woman or a man, plays a central role in health. However, there are so far few approaches to quantify gender in a retrospective manner in existing study datasets. We therefore aimed to develop a methodology that...

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Published in:Biology of sex differences 2021-01, Vol.12 (12), p.15-10, Article 15
Main Authors: Nauman, Ahmad Tauseef, Behlouli, Hassan, Alexander, Nicholas, Kendel, Friederike, Drewelies, Johanna, Mantantzis, Konstantinos, Berger, Nora, Wagner, Gert G, Gerstorf, Denis, Demuth, Ilja, Pilote, Louise, Regitz-Zagrosek, Vera
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Language:English
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Summary:In addition to biological sex, gender, defined as the sociocultural dimension of being a woman or a man, plays a central role in health. However, there are so far few approaches to quantify gender in a retrospective manner in existing study datasets. We therefore aimed to develop a methodology that can be retrospectively applied to assess gender in existing cohorts. We used baseline data from the Berlin Aging Study II (BASE-II), obtained in 2009–2014 from 1869 participants aged 60 years and older. We identified 13 gender-related variables and used them to construct a gender score by using primary component and logistic regression analyses. Of these, nine variables contributed to a gender score: chronic stress, marital status, risk-taking behaviour, personality attributes: agreeableness, neuroticism, extraversion, loneliness, conscientiousness, and level of education. Females and males differed significantly in the distribution of the gender score, but a significant overlap was also found. Thus, we were able to develop a gender score in a retrospective manner from already collected data that characterized participants in addition to biological sex. This approach will allow researchers to introduce the notion of gender retrospectively into a large number of studies.
ISSN:2042-6410
2042-6410
DOI:10.1186/s13293-020-00351-2