Is Systemic (Interstitial Fluid) Acidosis an Initial Event in the Etiopathogenesis of Dental Caries? A Hypothesis

Introduction: Dental caries is a microbial disease which affects retentive areas of the teeth. It has shown significant increase in incidence and prevalence in modern population. Various theories have been postulated in an attempt to explain the etiopathogenesis of dental caries. Despite their popul...

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Bibliographic Details
Published in:Dental hypotheses 2018-10, Vol.9 (4), p.96-100, Article 96
Main Authors: Tamgadge, Sandhya, Tamgadge, Avinash
Format: Article
Language:English
Subjects:
Acidosis
Acids
Bacterial infections
Body fluids
Bones
Cancer
Caries
Demineralization
Dental caries
Dentin
Dietary minerals
Enamel
Fluids
Hypotheses
hypothesis
Lead
Metabolism
Osteoporosis
Pathogenesis
pore volume
Researchers
Risk factors
systemic acidosis
Systemic diseases
Teeth
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Summary:Introduction: Dental caries is a microbial disease which affects retentive areas of the teeth. It has shown significant increase in incidence and prevalence in modern population. Various theories have been postulated in an attempt to explain the etiopathogenesis of dental caries. Despite their popularity, there are many questions which various theories haven't been able to answer. And still there is no definite cure for dental caries. Consequently, in most cases the process can't be reversed. Therefore, to tackle this issue other risk factors involved in the etiopathogenesis need to be explored. The Hypothesis: It could be suggested that there might be additional systemic factors, e.g. systemic acidosis, in pathogenesis of dental caries, in addition to proven localized causative factors. Evaluation of the Hypothesis: Various hypotheses have been discussed, on the basis of histopathology, and various research articles. The demineralization of bone osteoporosis and tooth demineralization of dental caries have been correlated to evaluate the hypothesis. Few parameters have been added in the proven local factors of etiopathogenesis of dental caries.
ISSN:2155-8213
2155-8213
DOI:10.4103/denthyp.denthyp_72_18