Comparison of Serum Lipid Profile in HIV Positive Patients on ART with ART Naïve Patients

The widespread use of effective highly active antiretroviral therapy (HAART) in HIV patients has coincided with increasing reports of complications like HIV-associated lipodystrophy syndrome and the metabolic alterations, affecting the lipid and glucose metabolism. Evidences in support of lipodystro...

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Bibliographic Details
Published in:Journal of clinical and diagnostic research 2014-10, Vol.8 (10), p.CC06-CC09
Main Authors: V, Indumati, V, Vijay, Shekhanawar, M S, Rajeshwari, M, Amareshwaras, D, Shantala
Format: Article
Language:English
Subjects:
Biochemistry Section
first line haart regimen
lipid profile
lipodystrophy syndrome
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Summary:The widespread use of effective highly active antiretroviral therapy (HAART) in HIV patients has coincided with increasing reports of complications like HIV-associated lipodystrophy syndrome and the metabolic alterations, affecting the lipid and glucose metabolism. Evidences in support of lipodystrophy and dyslipidaemia associated with First- line HAART in our area is scarce. The aim of the present study was 1) to study and compare Lipid profile in HIV positive patients on ART with that of freshly diagnosed HIV positive patients who were yet to be started on ART. 2) To assess lipodystrophy syndrome in patients on ART. Hundred newly diagnosed HIV positive patients who were yet to be started on ART were taken as controls (ART-Naïve).Hundred randomly selected HIV+ patients who were already on First-line ART regimen (Stavudine/Zudovudine + Lamivudine + Nevirapine) for more than 12 months were taken as cases (ART). This study was conducted for a period of 12 months at the VIMS ART centre, Bellary, Karnataka, India. There was a significant increase (p
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2014/9685.4979