Feasibility of an alternative, physiologic, individualized open-lung approach to high-frequency oscillatory ventilation in children

Background High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We ha...

Full description

Saved in:
Bibliographic Details
Published in:Annals of intensive care 2019-01, Vol.9 (1), p.9-13, Article 9
Main Authors: de Jager, Pauline, Kamp, Tamara, Dijkstra, Sandra K., Burgerhof, Johannes G. M., Markhorst, Dick G., Curley, Martha A. Q., Cheifetz, Ira M., Kneyber, Martin C. J.
Format: Article
Language:English
Subjects:
Acute respiratory failure
Anesthesiology
Child
Critical Care Medicine
Emergency Medicine
High-frequency oscillatory ventilation
Intensive
Intensive care
Mechanical ventilation
Medicine
Medicine & Public Health
Paediatric acute respiratory distress syndrome
Paediatrics
Pediatrics
Respiratory therapy
Severe acute respiratory syndrome
Ventilators
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We have adopted an open-lung HFOV strategy based on a corner frequency approach using an initial incremental–decremental mean airway pressure titration manoeuvre, a high frequency (8–15 Hz), and high power to initially target a proximal pressure amplitude (∆ P proximal ) of 70–90 cm H 2 O, irrespective of age or weight. Methods We reviewed prospectively collected data on patients
ISSN:2110-5820
2110-5820
DOI:10.1186/s13613-019-0492-0