Hyperchloremic Metabolic Acidosis due to Cholestyramine: A Case Report and Literature Review

Cholestyramine is a bile acid sequestrant that has been used in the treatment of hypercholesterolemia, pruritus due to elevated bile acid levels, and diarrhea due to bile acid malabsorption. This medication can rarely cause hyperchloremic nonanion gap metabolic acidosis, a complication featured in t...

Full description

Saved in:
Bibliographic Details
Published in:Case reports in nephrology 2015-01, Vol.2015 (2015), p.1-3
Main Authors: Kamar, Fareed B., McQuillan, Rory
Format: Article
Language:English
Subjects:
Acidification
Acids
Bile
Case Report
Colleges & universities
Kidneys
Literature reviews
Metabolism
Potassium
Urine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cholestyramine is a bile acid sequestrant that has been used in the treatment of hypercholesterolemia, pruritus due to elevated bile acid levels, and diarrhea due to bile acid malabsorption. This medication can rarely cause hyperchloremic nonanion gap metabolic acidosis, a complication featured in this report of an adult male with concomitant acute kidney injury. This case emphasizes the caution that must be taken in prescribing cholestyramine to patients who may also be volume depleted, in renal failure, or taking spironolactone.
ISSN:2090-6641
2090-665X
DOI:10.1155/2015/309791