Treatment outcome of different antiretroviral drug regimens in HIV-positive pregnant women

Objective: The objective of the study was to compare the maternal and fetal outcomes of currently preferred tenofovir-based regimen with previous zidovudine-based regimen and also to determine whether the time of starting antiretroviral therapy (ART), whether it can affect the pregnancy and fetal ou...

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Bibliographic Details
Published in:Perspectives in clinical research 2021-01, Vol.12 (1), p.40-47
Main Authors: Chauhan, Nidhi, Desai, Mira, Shah, Samidh, Shah, Asha, Gadhavi, Rajendra
Format: Article
Language:English
Subjects:
Antiretroviral drugs
antiretroviral therapy
Apgar score
Atazanavir
Birth weight
Body weight
cd4 count
Drug therapy
Efavirenz
Hemoglobin
Highly active antiretroviral therapy
HIV
HIV (Viruses)
Human immunodeficiency virus
Original
Patient outcomes
Pregnancy
Pregnant women
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Summary:Objective: The objective of the study was to compare the maternal and fetal outcomes of currently preferred tenofovir-based regimen with previous zidovudine-based regimen and also to determine whether the time of starting antiretroviral therapy (ART), whether it can affect the pregnancy and fetal outcome. Materials and Methods: Pregnant patients prescribed any of the above regimens were followed up every month till delivery and newborns for initial 6 months. Maternal endpoints were body weight, hemoglobin, and CD4 count, whereas fetal endpoints were birth weight, Apgar score, body weight, and HIV status at 6 months. Data were analyzed using ANOVA and unpaired t-test.P
ISSN:2229-3485
2229-5488
DOI:10.4103/picr.PICR_74_19