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A novel imaging index for predicting adverse progression in acute-on-chronic liver failure related to hepatitis B virus: the low erector spine index

It is widely known that muscle mass influences the outcomes of many chronic diseases. Erector spine mass is a convenient parameter obtained from routine abdominal computed tomography (CT). The clinical application value of erector spine mass, and whether erector spine mass could predict the outcome...

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Published in:BMC gastroenterology 2023-10, Vol.23 (1), p.1-367, Article 367
Main Authors: Zhou, Chao, Liu, Yuan, Liang, Xiaoxiao, Zhang, Ning, He, Tingting, Zhang, Jingjing, Zhang, Jin, Fu, Shuangnan, Li, Xin, Liu, Pengcheng, Zhang, Tianyi, Gong, Man
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Language:English
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Summary:It is widely known that muscle mass influences the outcomes of many chronic diseases. Erector spine mass is a convenient parameter obtained from routine abdominal computed tomography (CT). The clinical application value of erector spine mass, and whether erector spine mass could predict the outcome of disease has not been studied. To evaluate the role of the erector spine index (ESI) calculated based on abdominal CT imaging in the progression of acute-on-chronic liver failure related to the hepatitis B virus (HBV-ACLF). We performed a retrospective study of 118 HBV-ACLF patients and calculated the ESI (the total erector spine area normalized for height.sup.2 in meters) for each patient through abdominal CT. The findings were analyzed regarding the progression of HBV-ACLF and the ESI at baseline, including mortality and the development of complications. The ESI level was associated with mortality and the development of complications. During the 90-day follow-up period, patients with a low ESI (
ISSN:1471-230X
1471-230X
DOI:10.1186/s12876-023-02995-x