ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION

Objective: To compare the frequency of patients with successful Trial of voiding without catheter (TWOC) after acute urinary retention secondary to benign prostatic hyperplasia in patients taking ketoconazole and tamsulosin vs tamsulosin alone. Study Design: A randomized controlled trial. Place and...

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Bibliographic Details
Published in:Pakistan Armed Forces medical journal 2020-12, Vol.70 (6), p.1723-1727
Main Authors: Muhammad Asim, Syed Farhan Ahmed, Muhammad Sajid Ali, Imran Memon, Waqas Memon, Muhammad Rashid, Kiran Abbas, Moiz Ahmed
Format: Article
Language:English
Subjects:
acute urinary retention
benign prostatic hyperplasia
ketoconazole
tamsulosin
trial without catheter
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Summary:Objective: To compare the frequency of patients with successful Trial of voiding without catheter (TWOC) after acute urinary retention secondary to benign prostatic hyperplasia in patients taking ketoconazole and tamsulosin vs tamsulosin alone. Study Design: A randomized controlled trial. Place and Duration: The current study was conducted at Urology Ward, Liaquat National Hospital, Pakistan for a period of six months. Methodology: A total of 162 patients presenting with acute urinary retention were divided into two groups. Group A received tamsulosin 0.4mg OD and ketoconazole 200mg while Group B received tamsulosin and placebo. Trial of voiding without a catheter was induced after one week of medication. SPSS version 20 was used for data compilation and analysis. Results: In Group-A, 85.2% of patients were able to void as compared to group B, where only 74.1% of patients were able to void (p
ISSN:0030-9648
2411-8842
DOI:10.51253/pafmj.v70i6.3913