Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Hypertrophic Obstructive Cardiomyopathy Patients and Preserved Left Ventricular Ejection Fraction

Background In obstructive hypertrophic cardiomyopathy patients with preserved left ventricular (LV) ejection fraction, we sought to determine whether LV global longitudinal strain (LV‐GLS) provided incremental prognostic utility. Methods and Results We studied 1019 patients with documented hypertrop...

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Bibliographic Details
Published in:Journal of the American Heart Association 2017-10, Vol.6 (10), p.n/a
Main Authors: Tower‐Rader, Albree, Betancor, Jorge, Popovic, Zoran B., Sato, Kimi, Thamilarasan, Maran, Smedira, Nicholas G., Lever, Harry M., Desai, Milind Y.
Format: Article
Language:English
Subjects:
Adult
Biomechanical Phenomena
Cardiomyopathy, Hypertrophic - diagnostic imaging
Cardiomyopathy, Hypertrophic - mortality
Cardiomyopathy, Hypertrophic - physiopathology
Cardiomyopathy, Hypertrophic - therapy
Chi-Square Distribution
Echocardiography, Doppler
Female
Humans
hypertrophic cardiomyopathy
Kaplan-Meier Estimate
Male
Middle Aged
Multivariate Analysis
Myocardial Contraction
Nonlinear Dynamics
Original Research
outcome
Predictive Value of Tests
Proportional Hazards Models
Recovery of Function
Retrospective Studies
Risk Factors
strain
Stroke Volume
Time Factors
Treatment Outcome
Ventricular Function, Left
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Summary:Background In obstructive hypertrophic cardiomyopathy patients with preserved left ventricular (LV) ejection fraction, we sought to determine whether LV global longitudinal strain (LV‐GLS) provided incremental prognostic utility. Methods and Results We studied 1019 patients with documented hypertrophic cardiomyopathy (mean age, 50±12 years; 63% men) evaluated at our center between 2001 and 2011. We excluded age
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.117.006514