Efficacy of a combination of esafoxolaner, eprinomectin and praziquantel (NexGard ® Combo) against Thelazia callipaeda in naturally infected cats

This clinical study assessed the efficacy of a topical combination of esafoxolaner, eprinomectin and praziquantel (NexGard Combo) in treating cats naturally infected with the eyeworm Thelazia callipaeda (Nematoda, Thelaziidae). On Study Day (SD) 0, sixteen client-owned cats with eyeworm infection we...

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Bibliographic Details
Published in:Parasite (Paris) 2024, Vol.31, p.10-10
Main Authors: Di Cesare, Angela, Zanet, Stefania, Traversa, Donato, Colombo, Mariasole, Tielemans, Eric, Beugnet, Frederic, Ferroglio, Ezio
Format: Article
Language:English
Subjects:
cat
eprinomectin
nexgard® combo
thelazia callipaeda
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Summary:This clinical study assessed the efficacy of a topical combination of esafoxolaner, eprinomectin and praziquantel (NexGard Combo) in treating cats naturally infected with the eyeworm Thelazia callipaeda (Nematoda, Thelaziidae). On Study Day (SD) 0, sixteen client-owned cats with eyeworm infection were allocated to an untreated control group (G1, 8 cats) or to a NexGard Combo treated group (G2, 8 cats) and subjected to ocular examination. Cats in G2 received the treatment as per label recommendations. On SD 7 and 14 (±1), cats were examined for the presence of eyeworms and clinical signs. On SD 14, eyeworms were collected and counted. On SD 7 and 14, all cats in G1 were still infected with eyeworms, while G2 cats were free from eyeworms on SD 7 and 14, demonstrating 100% efficacy (p 
ISSN:1776-1042
1252-607X
1776-1042
DOI:10.1051/parasite/2024008