Correlation Study Between HCV Genotypes Distribution Pattern and Viral Load in a Tertiary Care Hospital in Kolkata, India

Hepatitis C virus infection is a leading cause for chronic liver disease. It has wide population specific genotype variability. Genotype knowledge and viral load assessment are equally important for designing therapeutic strategies and as predictors of treatment outcome among hepatitis C (HCV) infec...

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Bibliographic Details
Published in:Journal of clinical and diagnostic research 2015-05, Vol.9 (5), p.DC15-DC17
Main Authors: Bhattacharjee, Debojyoti, Mukherjee, Kheya, Chakroborti, Goutam, Ghosh, Ranadeep, Mandal, Nabarun, Bose, Mohua
Format: Article
Language:English
Subjects:
pcr
viral genotype
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Summary:Hepatitis C virus infection is a leading cause for chronic liver disease. It has wide population specific genotype variability. Genotype knowledge and viral load assessment are equally important for designing therapeutic strategies and as predictors of treatment outcome among hepatitis C (HCV) infected patients. Between June 2012 and 2013 an observational study was conducted among 350 chronic hepatitis patients visiting Calcutta National Medical College, Kolkata, India. Among them, 110 anti-HCV antibody positive cases were diagnosed and subjected to viral RNA extraction, viral genotyping and viral load quantification using polymerase chain reaction (PCR) based techniques. Statistical analysis was done with IBM SPSS Statistics software, version 20. p-value
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2015/12701.5977