Ocular Manifestations of Sarcoidosis in a South Florida Population

• Published in: Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2020-01, Vol.14, p.3741-3746
• Main Authors: Laura, Diana, Lee, Yonghoon, Farhangi, Monika, Salamo, Oriana, Mirsaeidi, Mehdi, Goldhardt, Raquel, Galor, Anat
• Format: Article
• Language: English
• Subjects: African Americans; Age; Biopsy; Edema; Ethnicity; Eye diseases; Glaucoma; Granulomas; Hispanic Americans; Medical imaging; neurosarcoidosis; Ocular manifestations of general diseases; ocular sarcoidosis; Original Research; Patients; Population; Risk factors; Sarcoidosis; Statistical analysis; uveitis; White people
• ISSN: 1177-5467; 1177-5483; 1177-5483
• DOI: 10.2147/OPTH.S278373

To describe the ocular manifestations of sarcoidosis in a South Florida population and identify risk factors for the presence of ocular disease. Retrospective consecutive case series. Medical charts of individuals with sarcoidosis seen in the University of Miami pulmonary department were reviewed for ocular disease. Odds ratios were used to identify risk factors for ocular sarcoidosis. Fourteen of 108 individuals with sarcoidosis had ocular involvement. The mean age of the 14 individuals was 56±15 years. Seventy-one percent were female, 50% were black, and 21% were Hispanic. Twelve had uveitis of which panuveitis was the most common subtype. Five had ≤20/70 vision in at least one eye due to uveitis. Neurosarcoidosis was a risk factor for ocular sarcoidosis (OR 6.14, p=0.03, 95% CI 1.21-31.09). Ocular manifestations occurred in a minority of individuals in a pulmonary sarcoidosis clinic in South Florida. Uveitis was the most common ocular manifestation. Neurosarcoidosis was a risk factor for ocular involvement.