Correlation between body mass index and gender-specific 28-day mortality in patients with sepsis: a retrospective cohort study

To investigate the potential correlation between body mass index (BMI) and the 28-day mortality rate among sepsis patients and the gender difference in this association. The current research was a retrospective cohort study. A total of 14,883 male and female cohorts of sepsis patients were included...

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Bibliographic Details
Published in:Frontiers in medicine 2024-10, Vol.11, p.1462637
Main Authors: Li, Chong, Huang, Huaping, Xia, Qingjie, Zhang, Li
Format: Article
Language:English
Subjects:
body mass index
gender
Medicine
mortality
obesity
sepsis
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Summary:To investigate the potential correlation between body mass index (BMI) and the 28-day mortality rate among sepsis patients and the gender difference in this association. The current research was a retrospective cohort study. A total of 14,883 male and female cohorts of sepsis patients were included in the Medical Information Mart for Intensive Care IV (MIMIC-IV V2.2) database. Patients in each gender cohort were further classified as underweight, normal weight, overweight, or obese according to BMI and the World Health Organization (WHO) BMI categories. The 28-day mortality from the date of ICU hospitalization was the primary outcome measure. The BMI and 28-day mortality exhibited an L-shaped relationship ( for nonlinearity
ISSN:2296-858X
2296-858X
DOI:10.3389/fmed.2024.1462637