Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Fresh Look at an Old Foe

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are some of the less common cutaneous adverse drug reactions with significant mortality. This study was undertaken with the objective of studying the demographics and clinical profile of SJS/TEN and identifying parameters associated...

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Bibliographic Details
Published in:Indian journal of dermatology 2023-01, Vol.68 (1), p.34-40
Main Authors: Kaimal, Sowmya, Lobo, Carol, Narayan, Girish, Augustine, Mary
Format: Article
Language:English
Subjects:
Antibiotics
Armodafinil
Complications and side effects
cutaneous adverse drug reactions
drug rash
Evidence-based medicine
India
Intensive care
Medical records
Methicillin
Mortality
Original
Patients
Stevens-Johnson syndrome
toxic epidermal necrolysis
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Summary:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are some of the less common cutaneous adverse drug reactions with significant mortality. This study was undertaken with the objective of studying the demographics and clinical profile of SJS/TEN and identifying parameters associated with mortality. All patients with SJS/TEN over 10 years (2010-2020) were included in the study. Data obtained from in-patient and out-patient records were analysed. A total of 82 patients with SJS/TEN were admitted to our centre over a period of 10 years. Patients with SJS were significantly younger than those with TEN, with a male: female ratio >1 in SJS and
ISSN:0019-5154
1998-3611
DOI:10.4103/ijd.ijd_726_22