Community versus academic hospital community-acquired pneumonia patients: a nested cohort study

• Published in: Pneumonia 2024-11, Vol.16 (1), p.31-9, Article 31
• Main Authors: Tsang, Jennifer L Y, Rego, Kian, Binnie, Alexandra, Lee, Terry, Mccarthy, Anne, Cowan, Juthaporn, Archambault, Patrick, Lellouche, Francois, Turgeon, Alexis F, Yoon, Jennifer, Lamontagne, Francois, Mcgeer, Allison, Douglas, Josh, Daley, Peter, Fowler, Robert, Maslove, David M, Winston, Brent W, Lee, Todd C, Tran, Karen C, Cheng, Matthew P, Vinh, Donald C, Boyd, John H, Walley, Keith R, Singer, Joel, Marshall, John C, Haljan, Gregory, Jain, Fagun, Russell, James A
• Format: Article
• Language: English
• Subjects: Community hospital; Community-acquired pneumonia; Corticosteroids; Mortality
• ISSN: 2200-6133; 2200-6133
• DOI: 10.1186/s41479-024-00143-x

Most Canadians receive their care in community hospitals, yet most clinical research is conducted in academic hospitals. This study aims to compare patients with community acquired pneumonia (CAP) treated in academic and community hospitals with respect to their demographics, clinical characteristics, treatments and outcomes. This nested observational cohort substudy of the Community Acquired Pneumonia: Toward InnoVAtive Treatment (CAPTIVATE) trial included 1,329 hospitalized adults with CAP recruited between March 1st, 2018 and September 31st, 2023 from 15 Canadian hospitals. Unadjusted and adjusted analyses for age, sex and co-morbidities using logistic, Cox and censored quantile regressions were conducted. Patients in community hospitals were older (mean [SD] 75.0 [15.7] years vs. 68.3 [16.2] years; p